Results 41 to 50 of about 1,055,977 (218)

Stress-induced tradeoffs in a free-living lizard across a variable landscape: consequences for individuals and populations. [PDF]

PLoS ONE, 2012
Current life history theory suggests that the allocation of energetic resources between competing physiological needs should be dictated by an individual's longevity and pace of life. One key physiological pathway likely to contribute to the partitioning
Leilani D Lucas, Susannah S French
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Identification of Resilient Individuals and Those at Risk for Performance Deficits under Stress

Frontiers in Neuroscience, 2015
Human task performance is affected by exposure to physiological and psychological stress. The ability to measure the physiological response to stressors and correlate that to task performance could be used to identify resilient individuals or those at ...
Brent eWinslow, Meredith B Carroll, Jonathan W Martin, Glenn eSurpris, George L Chadderdon   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Impact of 24 h shifts on urinary catecholamine in emergency physicians: a cross-over randomized trial

Scientific Reports
24-h shift (24 hS) exposed emergency physicians to a higher stress level than 14-h night shift (14 hS), with an impact spreading on several days. Catecholamines are supposed to be chronic stress biomarker.
Frédéric Dutheil, Alicia Fournier, Christophe Perrier, Damien Richard, Marion Trousselard, George Mnatzaganian, Julien S. Baker, Reza Bagheri, Martial Mermillod, Maelys Clinchamps, Jeannot Schmidt, Jean-Baptiste Bouillon-Minois   +11 more
doaj   +1 more source

Psychosocial well-being index and sick leave in the workplace: a structural equation modeling of Wittyfit data

Frontiers in Psychology
BackgroundPsychosocial well-being, which assesses emotional, psychological, social, and collective well-being, could help measure risk and duration of sick leave in workers.ObjectiveThis study aims to build a structural equation model of a psychosocial ...
Rémi Colin-Chevalier, Bruno Pereira, Samuel Dewavrin, Thomas Cornet, Julien Steven Baker, Frédéric Dutheil   +5 more
doaj   +1 more source

Physiological dynamics of stress contagion

Scientific Reports, 2017
Can viewing others experiencing stress create a “contagious” physiological stress response in the observer? To investigate second-hand stress, we first created a stimulus set of videos, which featured participants speaking under either minimal stress ...
Stephanie J. Dimitroff, Omid Kardan, Elizabeth A. Necka, Jean Decety, Marc G. Berman, Greg J. Norman   +5 more
doaj   +1 more source

The impact of sugar-sweetened beverage intake on rat cardiac function

Heliyon, 2019
Aims: Although there is evidence linking sugar-sweetened beverage (SSB) intake with the development of cardio-metabolic diseases, the underlying mechanisms remain unclear.
Natasha Driescher, Danzil E. Joseph, Veronique R. Human, Edward Ojuka, Martin Cour, Nkanyiso Hadebe, Dirk Bester, Jeanine L. Marnewick, Sandrine Lecour, Amanda Lochner, M. Faadiel Essop   +10 more
doaj   +1 more source