Results 41 to 50 of about 1,096,962 (313)

Stress-induced tradeoffs in a free-living lizard across a variable landscape: consequences for individuals and populations. [PDF]

PLoS ONE, 2012
Current life history theory suggests that the allocation of energetic resources between competing physiological needs should be dictated by an individual's longevity and pace of life. One key physiological pathway likely to contribute to the partitioning
Leilani D Lucas, Susannah S French
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Study of the stress of parents of patients with cleft lip and palate in a surgical process

Estudos de Psicologia (Campinas)
Family with children affected by genetic factors or teratogenics involving functional, aesthetic and psychological sequels such as cleft lip and palate are vulnerable to several stress levels and need corrective and rehabilitation interventions.
Maria de Lourdes Merighi Tabaquim, Matilde Aparecida Motta Marquesini   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Exploring the relationship between occupational stress, physical activity and sedentary behavior using the Job-Demand-Control Model

Frontiers in Public Health
ObjectivesTo study the relationship between the occupational stress model, specifically the Job Demand-Control Model of Karasek, physical activity level and sedentary behavior.MethodThis is a cross-sectional, observational, descriptive study.
Maëlys Clinchamps, Céline Bibily, Jean-Baptiste Bouillon-Minois, Ukadike C. Ugbolue, Marion Trousselard, Bruno Pereira, Frédéric Dutheil   +6 more
doaj   +1 more source

Does Cardiorespiratory Fitness Buffer Stress Reactivity and Stress Recovery in Police Officers? A Real-Life Study

Frontiers in Psychiatry, 2020
High levels of cardiorespiratory fitness have the potential to buffer against physical and mental health impairments, which can result from exposure to occupational stress.
René Schilling, Christian Herrmann, Sebastian Ludyga, Flora Colledge, Serge Brand, Serge Brand, Serge Brand, Serge Brand, Serge Brand, Uwe Pühse, Markus Gerber   +10 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Indicators of physiological stress and the elaboration of sexual traits in the collared flycatcher

, 2006
Stress may have consequences for the evolution of condition-dependent sexual traits. For example, stress may be related to sexual traits through immune function, and sexual traits can reflect how individuals bear the costs of stress-mediated ...
Török, János, Marcel Eens, T\uf6r\uf6k, J\ue1nos, Santiago Merino, János Török, László Zsolt Garamszegi, Eens, Marcel, Martínez, Javier, Javier Martínez, Merino, Santiago, Mart\uednez, Javier, Garamszegi, L\ue1szl\uf3, Garamszegi, László Zsolt   +12 more
core   +1 more source

Evaluating cognitive bias in clinical ethics supports: a scoping review

BMC Medical Ethics
Background A variety of cognitive biases are known to compromise ethical deliberation and decision-making processes. However, little is known about their role in clinical ethics supports (CES).
Louise Giaume, Antoine Lamblin, Nathalie Pinol, Frédérique Gignoux-Froment, Marion Trousselard   +4 more
doaj   +1 more source