Results 71 to 80 of about 697,108 (267)

Pore pressures and strains after repeated loading of saturated clay [PDF]

open access: yes, 1974
Repeated and sustained loading tests on undrained samples of normally consolidated lacustrine clay are used to prove the existence of a relationship between pore water pressures and axial strains.The behavior of the clay is studied by investigating the ...
Greenwood, JR   +3 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Determining the effect of strain rate on the fracture of sheet steel [PDF]

open access: yes
A key challenge for the automotive industry is to reduce vehicle mass without compromising on crash safety. To achieve this, it is necessary to model local failure in a material rather than design to the overly conservative criteria of total elongation
Beaumont, Richard Adrian
core  

Synchrotron strain scanning for residual stress measurement in cold-drawn steel rods

open access: yes, 2011
Cold-drawn steel rods and wires retain significant residual stresses as a consequence of the manufacturing process. These residual stresses are known to be detrimental for the mechanical properties of the wires and their durability in aggressive ...
M Elices   +5 more
core   +1 more source

Identification of plastic constitutive parameters at large deformations from three dimensional displacement fields [PDF]

open access: yes, 2011
The aim of this paper is to provide a general procedure to extract the constitutive parameters of a plasticity model starting from displacement measurements and using the Virtual Fields Method.
Fabrice Pierron   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Debbie Strain Oral History

open access: yes, 1990
Debbie Strain is interviewed by Vanessa Langhurst about her experiences at Columbus State Community ...
Debbie Strain
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

The Application of the Stress Function Eri for Nuclear Reactor’s Fuel Elements Strain Analysis

open access: yesМеханика машин, механизмов и материалов, 2010
The mathematical-mechanical models for describe steady stressstrain state of the nuclear reactors fuel pins are proposed. The possibility of the application stress function Eri for determining stress-strain state of the atomic power station's fuel pins ...
I.S. Kulikov , P.I. Shirvel'
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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