Results 81 to 90 of about 1,214,541 (261)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The Application of the Stress Function Eri for Nuclear Reactor’s Fuel Elements Strain Analysis
Механика машин, механизмов и материалов, 2010 The mathematical-mechanical models for describe steady stress strain state of the nuclear reactors fuel pins are proposed. The possibility of the application stress function Eri for determining stress-strain state of the atomic power station's fuel pins ...
I.S. Kulikov , P.I. Shirvel'
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Identification of plastic constitutive parameters at large deformations from three dimensional displacement fields [PDF]
, 2012 The aim of this paper is to provide a general procedure to extract the constitutive parameters of a plasticity model starting from displacement measurements and using the Virtual Fields Method.
A Bertram +59 more
core +5 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Study of stress-strain state of the roller conveyor
Metalurgija, 2022 Numerous studies have established that the damage to the lower surface of hot-rolled strips is mainly due to their friction against rollers of mill rollers. In this case, the probability of scoring, scrapes and other mechanical damage increases otherwise
D. Yergaliyev +7 more
doaj
Modeling and Model Verification of the Stress-Strain State of Reinforced Polymer Concrete. [PDF]
Materials (Basel), 2023 Yelemessov K +5 more
europepmc +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Observations of fatigue crack nucleation and early growth are presented. The state of stress/strain was shown to play a significant role in this process.
Socie, Darrell
core +1 more source
Modeling the microstructural evolution during constrained sintering [PDF]
, 2014 A numerical model able to simulate solid-state constrained sintering is presented. The model couples an existing kinetic Monte Carlo (kMC) model for free sintering with a finite element model (FEM) for calculating stresses on a microstructural level. The
Bjørk, R., Frandsen, H. L., Pryds, N.
core +4 more sources