Results 61 to 70 of about 31,042,989 (282)

Stress-strain state of the precast monolithic bent element

open access: yesИнженерно-строительный журнал, 2020
The features of the stress-strain state of a precast monolithic bent element (beam) arising as a result of its phased installation and loading are considered and experimentally investigated.
Alexandr Koyankin, Valery Mitasov
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Early Warning Model of Pipeline Stress State Based on Axial Stress Monitoring Data

open access: yesShiyou jixie, 2018
To manage the stress state of the pipeline in real time and take timely targeted measures, stress monitoring measures are usually taken for pipelines that are prone to displacement deformation.
Liu Yuqing   +3 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Investigation of the Behaviour of Cohesive Powder in the Biaxial Tester

open access: yesKONA Powder and Particle Journal, 2014
The results from experiments with cohesive limestone powder in a Biaxial Tester are presented. The biaxial tester allows a plane homogeneous deformation and measurement of the complete stress-strain states.
Hermann Josef Feise, Jörg Schwedes
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Construction and application of the limit strain surface for evaluating the plasticity of porous bodies

open access: yesПроблеми трибології
Traditional failure criteria for solid materials are not applicable to powder materials due to the presence of porosity, which acts as a sink for dislocations, alters defect accumulation kinetics, and slows structural degradation.
R. Sivak   +4 more
doaj   +1 more source

Comparison of the stress and strain intensity factors for the corner area of the structure boundary

open access: yesMATEC Web of Conferences, 2018
The stress-strain state of structures in areas with corner cut-outs and cuts of boundaries features the occurrence of areas of stress concentration and requires assessment of strength and reliability of facilities, which is a relevant task in engineering
Frishter Lyudmila
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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