Results 61 to 70 of about 1,214,541 (261)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Finite element modelling of contact interaction between wheel and rail with three-layered thin coating [PDF]

open access: yesTransport Problems, 2010
The stress-strain of thin multilayered coatings covered the surface of the rail is studied near the region of side contact in turning motion. The stress-strain state is studied for various geometric and mechanical coating parameters’ values.
Vladimir KOLESNIKOV   +3 more
doaj  

Deformability parameters for forming the stress-strain state models of rock massif [PDF]

open access: yesMining and Metallurgy Engineering Bor, 2013
This paper describes the principle of development the structural models of rocks, based on which the geomechanical model rock massif is developed, to which the applied numerical methods of stress analysis can be applied in solving the practical problems ...
Popović Ratomir   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Stress-strain state of bending reinforced beams with cracks

open access: yesИнженерно-строительный журнал, 2020
The work is dealing with studying the stress-strain state of bending pre-stressed concrete beams with cracks. The problems of determining preliminary stresses in a reinforced concrete element, determining the moment of crack formation, and determining ...
Omirkhan Khabidolda   +5 more
doaj   +1 more source

Experimental Study on Thermal Expansion Behavior of Concrete under Three-Dimensional Stress

open access: yesAdvances in Civil Engineering, 2021
Concrete is widely used in underground engineering and bears three-dimensional stress transmitted by overlying load. When a fire occurs, the thermal expansion of concrete structure under such stress state is different from that under stress-free state ...
Zhipeng Yu   +5 more
doaj   +1 more source

Modelling plasticity of unsaturated soils in a thermodynamically consistent framework [PDF]

open access: yes, 2009
Constitutive equations of unsaturated soils are often derived in a thermodynamically consistent framework through the use a unique 'effective' interstitial pressure. This later is naturally chosen as the space averaged interstitial pressure.
Coussy, O., Pereira, Jean-Michel
core   +3 more sources

An elastoplastic framework for granular materials becoming cohesive through mechanical densification. Part II - the formulation of elastoplastic coupling at large strain

open access: yes, 2010
The two key phenomena occurring in the process of ceramic powder compaction are the progressive gain in cohesion and the increase of elastic stiffness, both related to the development of plastic deformation.
Alessandro Gajo   +28 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Stress Path Dependence of Mechanical Properties of Saturated Soft Loess and its Simulation

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] The saturated soft loess formed by the rise of groundwater level is mostly in a soft plastic and flow plastic state, with engineering geological characteristics of high water content, high compression, and low bearing capacity.
LI Shixiong   +4 more
doaj   +1 more source

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