Results 61 to 70 of about 592,094 (302)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Scaffolds with a Tunable Nonlinear Elastic Region Using a Corrugated Design
Small StructuresElastin is the main component of arteries and is responsible for their high‐elastic high‐strain capacity. The biomechanics of biological tissues typically display a stress–strain curve characterized by a sigmoidal shape that has an initial region with ...
Kenny A. van Kampen +3 more
doaj +1 more source
Overshoots in stress strain curves: Colloid experiments and schematic mode coupling theory
, 2012 The stress versus strain curves in dense colloidal dispersions under start-up shear flow are investigated combining experiments on model core-shell microgels, computer simulations of hard disk mixtures, and mode coupling theory. In dense fluid and glassy
Amann, Christian P. +5 more
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Numerical study of the influence of the specimen geometry on split Hopkinson bar tensile test results [PDF]
, 2009 Finite element simulations of high strain rate tensile experiments oil sheet materials using different specimen geometries are presented. The simulations component ail experimental study, using a split Hopkinson tensile bar set-up, Coupled with a.
Degrieck, Joris +3 more
core
Activated dynamics and effective temperature in a steady state sheared glass
, 2007 We conduct nonequilibrium molecular dynamics simulations to measure the shear stress, the average inherent structure energy, and the effective temperature $T_{eff}$ of a sheared model glass as a function of bath temperature $T$ and shear strain rate. For
Andrea J. Liu +3 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Evaluation of Mechanical Parameters of Pellets
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016 The paper dealt with the evaluation of mechanical properties of the cylinder wheat straw, rapeseed straw and 50/50 % mixed wheat and rapeseed straw pellet samples. The pellets were made by the granulating machine MGL 200 (Kovonovak).
Ľubomír Kubík +2 more
doaj +1 more source
On cyclic yield strength in definition of limits for characterisation of fatigue and creep behaviour [PDF]
, 2017 This study proposes cyclic yield strength as a potential characteristic of safe design for structures operating under fatigue and creep conditions.
Gorash, Yevgen, MacKenzie, Donald
core +1 more source
Modified hydraulic bulging in acquisition of stress strain curve [PDF]
International Journal of Material Forming, 2010 From classical hydraulic bulging of a circular diaphragm, a new method of recording a stress-strain curve is derived named modified hydraulic bulging on the sphere. New method allows more accurate determination of membrane stress in the deforming material.
Grizelj, Branko +2 more
openaire +2 more sources