Results 71 to 80 of about 1,214,562 (306)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Strain-Stress State of Wood During Drying Process

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2013
The paper proposes theoretical and experimental methods for investigation of strain-stress state of wood and lumber saw-timbers in the process of heated-air drying.
V. A. Sychevsky
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Stress Path Dependence of Mechanical Properties of Saturated Soft Loess and its Simulation

Taiyuan Ligong Daxue xuebao
[Purposes] The saturated soft loess formed by the rise of groundwater level is mostly in a soft plastic and flow plastic state, with engineering geological characteristics of high water content, high compression, and low bearing capacity.
LI Shixiong, ZHANG Dengfei, ZHANG Xiaohui, CHEN Hanjiang, WANG Yonghua   +4 more
doaj   +1 more source

Deformability parameters for forming the stress-strain state models of rock massif [PDF]

Mining and Metallurgy Engineering Bor, 2013
This paper describes the principle of development the structural models of rocks, based on which the geomechanical model rock massif is developed, to which the applied numerical methods of stress analysis can be applied in solving the practical problems ...
Popović Ratomir, Ljubojev Milenko, Đurđevac-Ignjatović Lidija   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Modelling plasticity of unsaturated soils in a thermodynamically consistent framework [PDF]

, 2009
Constitutive equations of unsaturated soils are often derived in a thermodynamically consistent framework through the use a unique 'effective' interstitial pressure. This later is naturally chosen as the space averaged interstitial pressure.
Coussy, O., Pereira, Jean-Michel
core   +3 more sources

Stress-strain state of concrete element with damage

Bulletin of Prydniprovs’ka State Academy of Civil Engineering and Architecture, 2020
Problem statement. At present, it is relevant to determine the technical condition of structures and their strengthening as needed. Damage of structures affects the process of determining the physical and mechanical characteristics of concrete structures.  Purpose.
Kolokhov, V. V., Sopilniak, M. A., Mospan, V. І.   +2 more
openaire   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Correlations Between Metallurgical Characterization Studies, Exploratory Mechanical Tests, and Continuum Mechanics Approaches to Constitutive Equations [PDF]

, 1983
Austenitic stainless steels, such as types 316 and 304, are widely used as pressure vessel materials in the temperature range of 425 to 650 C. Stainless steel specimens were tested to rupture at two different stress levels sigma and sigma 2 sigma 1 sigma
Moteff, J., Pugh, C. E., Swindeman, R. W.   +2 more
core   +1 more source