Results 71 to 80 of about 697,180 (312)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
On Prediction of 3d Stress State in Elastic Shell by Higher-order Shell Formulations [PDF]
, 2008 In this work we study the accuracy of modem higher-order shell finite element formulations in computation of 3d stress state in elastic shells. In that sense we compare three higher-order shell models: (i) with seven dislacement-like kinematic parameters,
Brank, Boštjan +2 more
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Tensorial stress-plastic strain fields in α-ω Zr mixture, transformation kinetics, and friction in diamond anvil cell [PDF]
, 2022 Various phenomena (phase transformations, chemical reactions, and friction) under high pressures in diamond anvil cell are strongly affected by fields of all components of stress and plastic strain tensors. However, they could not be measured.
Levitas, Valery +2 more
core +1 more source
Experimental Study on Thermal Expansion Behavior of Concrete under Three-Dimensional Stress
Advances in Civil Engineering, 2021 Concrete is widely used in underground engineering and bears three-dimensional stress transmitted by overlying load. When a fire occurs, the thermal expansion of concrete structure under such stress state is different from that under stress-free state ...
Zhipeng Yu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Effects of principal stress rotation and drainage on the resilient stiffness of railway foundations [PDF]
, 2013 Railway foundations play an integral role in controlling the stability of the overlying track structure and the maintenance of the overall track geometry.
Mamou, A.
core
Stress Path Dependence of Mechanical Properties of Saturated Soft Loess and its Simulation
Taiyuan Ligong Daxue xuebao[Purposes] The saturated soft loess formed by the rise of groundwater level is mostly in a soft plastic and flow plastic state, with engineering geological characteristics of high water content, high compression, and low bearing capacity.
LI Shixiong +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Stress--strain state of the sclera and cornea as orthotropic non-uniform conjugated spherical shells [PDF]
, 2008 The stress–strain state of the conjugated orthotropic spherical shells under internal pressure is determined in this paper. A behavior of a corneoscleral shell of an eye with increasing of intraocular pressure can be modelled.
Ermakov, A. M.
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Stress–singularity analysis in space junctions of thin plates [PDF]
, 2000 The stress singularity in space junctions of thin linearly elastic isotropic plate elements with zero bending rigidities is investigated. The problem for an intersection of infinite wedge-shaped elements is considered first and the solution for each ...
Mikhailov, SE, Namestnikova, IV
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