Results 81 to 90 of about 697,180 (312)
Stress-strain state of concrete element with damage
Bulletin of Prydniprovs’ka State Academy of Civil Engineering and Architecture, 2020 Problem statement. At present, it is relevant to determine the technical condition of structures and their strengthening as needed. Damage of structures affects the process of determining the physical and mechanical characteristics of concrete structures. Purpose.
Kolokhov, V. V. +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Relaxation of thermal stress by dislocation motion in passivated metal interconnects [PDF]
, 2004 The development and relaxation of stress in metal interconnects strained by their surroundings (substrate and passivation layers) is predicted by a discrete dislocation analysis.
Giessen, Erik van der, +9 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Identification of damage in composite materials using thermoelastic stress analysis [PDF]
, 2007 A quantitative damage assessment methodology for composite materials has beenachieved using Thermoelastic Stress Analysis (TSA). The TSA technique provides fullfielddata which is collected in a non-contacting and real time manner.
Emery, Trystan Ross
core
Pore pressures and strains after repeated loading of saturated clay [PDF]
, 1974 Repeated and sustained loading tests on undrained samples of normally consolidated lacustrine clay are used to prove the existence of a relationship between pore water pressures and axial strains.The behavior of the clay is studied by investigating the ...
Greenwood, JR +3 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Determining the effect of strain rate on the fracture of sheet steel [PDF]
A key challenge for the automotive industry is to reduce vehicle mass without compromising on crash safety. To achieve this, it is necessary to model local failure in a material rather than design to the overly conservative criteria of total elongation
Beaumont, Richard Adrian
core
Identification of plastic constitutive parameters at large deformations from three dimensional displacement fields [PDF]
, 2011 The aim of this paper is to provide a general procedure to extract the constitutive parameters of a plasticity model starting from displacement measurements and using the Virtual Fields Method.
Fabrice Pierron +4 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source