Results 61 to 70 of about 434,967 (262)
Finite element modelling of contact interaction between wheel and rail with three-layered thin coating [PDF]
Transport Problems, 2010 The stress-strain of thin multilayered coatings covered the surface of the rail is studied near the region of side contact in turning motion. The stress-strain state is studied for various geometric and mechanical coating parameters’ values.
Vladimir KOLESNIKOV +3 more
doaj
Metalurgija, 2023 The article presents the results of improving the method of controlling the stress-strain state of steel structures of mine hoisting machines, which can be attributed to electromechanical systems.
A. B. Zhantlessova +7 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Strain-Stress State of Wood During Drying Process
Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2013 The paper proposes theoretical and experimental methods for investigation of strain-stress state of wood and lumber saw-timbers in the process of heated-air drying.
V. A. Sychevsky
doaj
Stress-strain state of earth dam under harmonic effect [PDF]
E3S Web of Conferences, 2019 Stress-strain state of earth dams under the effect of harmonic (seismic) load from the base of the dam is numerically studied in the paper. Rock fill dam has good culvert properties and its water saturation is considered to have no effect on mechanical ...
Khusanov Bakhtiyar, Khaydarova Ozodakhon
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Stress Path Dependence of Mechanical Properties of Saturated Soft Loess and its Simulation
Taiyuan Ligong Daxue xuebao[Purposes] The saturated soft loess formed by the rise of groundwater level is mostly in a soft plastic and flow plastic state, with engineering geological characteristics of high water content, high compression, and low bearing capacity.
LI Shixiong +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Control of the Stress-Strain State of an Undermined Mass
Procedia Structural Integrity, 2021 Abstract This paper introduces the mathematical modelling method of geomechanical processes, for which the parameters are provided by surface displacement surveys and seismic data.
openaire +1 more source