Results 61 to 70 of about 697,180 (312)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Yielding of unsaturated soil. [PDF]

open access: yes, 1994
Considerable efforts have been made in recent years to develop a better understanding of the mechanical behaviour of unsaturated soils in terms of elastoplastic critical state constitutive models.
Zakaria, Ideris
core  

Strain-Stress State of Wood During Drying Process

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2013
The paper proposes theoretical and experimental methods for investigation of strain-stress state of wood and lumber saw-timbers in the process of heated-air drying.
V. A. Sychevsky
doaj  

Some Approaches to Quantitative Classification of Plastic Deformation Processes Based on the Parameters of Their Stress–Strain State Determined by Simulation Modeling

open access: yesMetals
The article discusses the methods for classifying processes for testing and processing metals by plastic deformation, based on the characteristics of their stress–strain state.
Valentin Kamburov, Rayna Dimitrova
doaj   +1 more source

Stress-strain state of the precast monolithic bent element

open access: yesИнженерно-строительный журнал, 2020
The features of the stress-strain state of a precast monolithic bent element (beam) arising as a result of its phased installation and loading are considered and experimentally investigated.
Alexandr Koyankin, Valery Mitasov
doaj   +1 more source

Deformability parameters for forming the stress-strain state models of rock massif [PDF]

open access: yesMining and Metallurgy Engineering Bor, 2013
This paper describes the principle of development the structural models of rocks, based on which the geomechanical model rock massif is developed, to which the applied numerical methods of stress analysis can be applied in solving the practical problems ...
Popović Ratomir   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Finite element modelling of contact interaction between wheel and rail with three-layered thin coating [PDF]

open access: yesTransport Problems, 2010
The stress-strain of thin multilayered coatings covered the surface of the rail is studied near the region of side contact in turning motion. The stress-strain state is studied for various geometric and mechanical coating parameters’ values.
Vladimir KOLESNIKOV   +3 more
doaj  

Improving the method of controlling the stress-strain state of steel structures of electromechanical systems

open access: yesMetalurgija, 2023
The article presents the results of improving the method of controlling the stress-strain state of steel structures of mine hoisting machines, which can be attributed to electromechanical systems.
A. B. Zhantlessova   +7 more
doaj  

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