Results 121 to 130 of about 10,727,912 (338)

Stress and Quality of Life Among Parents of Children with Congenital Heart Disease Referred for Psychological Services [PDF]

open access: yes, 2018
Objective The study examined parent stress and health‐related quality of life (HRQOL) among families of children with congenital heart disease (CHD) referred for psychological services. Methods Parents of 54 children (85% boys) aged 3 to 13 (Mage = 7.48,
Brosig, Cheryl   +2 more
core   +1 more source

Modeling of torsion stress giant magnetoimpedance in amorphous wires with negative magnetostriction

open access: yes, 2007
A model describing the influence of torsion stress on the giant magnetoimpedance in amorphous wires with negative magnetostriction is proposed. The wire impedance is found by means of the solution of Maxwell equations together with the Landau-Lifshitz ...
Antonov   +39 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Can an Evaluation of Students’ Stress Levels Help us Manage Anxiety During OSCEs and Other Assessment Modalities? [PDF]

open access: yes, 2018
With an increased awareness of mental health issues, in both the student population and the veterinary profession in general, it is important that we obtain a greater understating of the stress experienced by students so as to better prepare them to deal
Dowell, Fiona   +5 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Distinct roles of histone H2B ubiquitination at promoters and coding regions of Pol II-transcribed stress genes

open access: yesGenome Biology
Background The histone code, comprised of diverse histone post-translational modifications, intricately regulates nucleosome organization and gene expression. Histone marks also serve as binding sites for a diverse array of protein complexes and enzymes,
Rubén Barrios   +7 more
doaj   +1 more source

Decreasing Caregiver Stress [PDF]

open access: yes, 2019
Stress is both critical and personal experience and has significant effects on caregivers’ physical, mental, and social well-being. The nature of caregiving and the responsibility to work and serve individuals at their illness conditions are very ...
Ramos, Dexter
core   +1 more source

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