Results 41 to 50 of about 2,653,921 (235)

Stress concentration investigations using NASTRAN [PDF]

open access: yes
Parametic investigations are performed using several two dimensional finite element formulations to determine their suitability for use in predicting extremum stresses in marine propellers. Comparisons are made of two NASTRAN elements (CTRIM6 and CTRAIA2)
Gillcrist, M. C., Parnell, L. A.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Stress concentrations in screw threads [PDF]

open access: yes
The concept of stress concentration in screw threads was defined using the sheer transfer rate as the fundamental quantity. The stress concentration is plotted for a fixed geometry.
Ohara, G. P.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Strategy of Nannochloropsis Against Environment Starvation: Population Density and Crude Lipid Contents [PDF]

open access: yes, 2013
Nannochloropsis sp., an unicellular marine microalgae, has potential function as a food source for fish larvae and in chemical industry. Microenvironmental conditions, especially nitrogen and salinity stress in marine ecosystems, became major factor ...
Hudaidah, S. (Siti)   +2 more
core  

Germination of primed seed under NaCl stress in wheat. [PDF]

open access: yes, 2012
Copyright © 2012 Michael P. Fuller et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Al Issawi, M   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A computational model for analysis of uncoupled NO synthase on nitric oxide and superoxide interaction in microcirculation [PDF]

open access: yes, 2007
Nitric oxide (NO) produced by endothelial cells is a key component for blood-vessel dilation. Dilation is achieved through smooth muscle relaxation as a response to NO transport.
Kavdia, Mahendra, Richardson, William
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Stress anisotropy and concentration effects in high pressure measurements [PDF]

open access: yes
Sodium chloride is used as an internal pressure standard in high pressure research. Possible corrections are discussed which are needed in the calibration of this standard due to the independent effects of stress anisotropy and stress concentration in ...
Nelson, D. A., Jr., Ruoff, A. L.
core   +1 more source

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