Results 51 to 60 of about 11,866,665 (347)

Fracture mechanics approach to design analysis of notches, steps and internal cut-outs in planar components

, 2007
A new approach to the assessment and optimization of geometric stress-concentrating features is proposed on the basis of the correspondence between sharp crack or corner stressfield intensity factors and conventional elastic stress concentration factors (
Gray, T.G.F., Wood, J.
core   +1 more source

Weld residual stress effects on fatigue crack growth behaviour of aluminium alloy 2024-T351 [PDF]

, 2008
The interaction between residual stress and fatigue crack growth rate has been investigated in middle tension and compact tension specimens machined from a variable polarity plasma arc welded aluminium alloy 2024-T351 plate.
Liljedahl, CDM, Tan, M. L., Edwards, Lyndon, Irving, PE, Brouard, J, Liljedahl, C.D.M., Zanellato, O., Fitzpatrick, M. E., Zhang, Xiang, Fitzpatrick, M.E., Brouard, J., Ganguly, S, Liljedahl, C. David M., Ganguly, S., Zanellato, O, Irving, P.E., Lin, J., Tan, ML, Liljedahl, C. D. M., Edwards, L., Fitzpatrick, Michael E., Zhang, X.; id_orcid, Ganguly, Supriyo, Zhang, X., Zhang, X, Edwards, L, Zanellato, Oliver, Lin, J, Irving, P. E., Irving, Phil E., Tan, M.L., Fitzpatrick, ME   +31 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Regional gas control scheme and effect analysis

Gong-kuang zidonghua, 2018
In view of problems of high gas pressure and poor permeability of outburst coal seam, unsatisfactory of outburst elimination effect of regional gas control, slow speed of coal roadway excavation and tension of working face replacement caused by deep ...
HU Zhifang
doaj   +1 more source

Stress concentration factors in FRP-strengthened steel tubular KT-joints

, 2021
This paper presents a brand new application of the fiber-reinforced polymer (FRP) materials as a strengthening tool for reinforcing offshore steel tubular KT-joints to reduce the stress concentration factors (SCFs).
Hosseini, Alireza Sadat, Ahmadi, Hamid, Sadat Hosseini, A, Zavvar, Esmaeil, Ahmadi, H, Zavvar, E   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effect of Salt Stress on Growth, Physiological Parameters, and Ionic Concentration of Water Dropwort (Oenanthe javanica) Cultivars

Frontiers in Plant Science, 2021
Salt stress is an important environmental limiting factor. Water dropwort (Oenanthe javanica) is an important vegetable in East Asia; however, its phenotypic and physiological response is poorly explored.
Sunjeet Kumar, Gaojie Li, Jingjing Yang, Xinfang Huang, Qun Ji, Zhengwei Liu, W. Ke, Hongwei Hou   +7 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source