Results 61 to 70 of about 11,866,665 (347)

Simulation of Stress Concentrations in Notches

Metals, 2021
The fatigue life curves of materials are very sensitive to the magnitude of the stress amplitude. A small change or inaccuracy in the determination of the stress value causes large changes or inaccuracies in the calculated fatigue life estimate ...
Vladimír Chmelko, Michal Harakaľ, Pavel Žlábek, Matúš Margetin, Róbert Ďurka   +4 more
doaj   +1 more source

Stress Concentration and Mechanical Strength of Cubic Lattice Architectures

Materials, 2018
The continuous design of cubic lattice architecture materials provides a wide range of mechanical properties. It makes possible to control the stress magnitude and the local maxima in the structure.
P. Lohmuller, J. Favre, B. Piotrowski, S. Kenzari, P. Laheurte   +4 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Concentration effects in the rheology of cement pastes: Krieger-Dougherty revisited [PDF]

, 2011
Cement pastes are concentrated suspensions of granular particles in water and their rheology strongly affects the behaviour of all concretes and other cementitious materials.
Banfill, Phillip Frank Gower
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A study on finite element of pre damaged stress concentration factor for a composite laminate member with central circular.

, 2018
The study investigates the pre damaged stress concentration factor (SCF) for a composite laminate member (CLM) with central circular hole subjected to tensile loading.
Choudhry, Rizwan Saeed, Shah, Atta Ur Rehman, Saeed, Hasan Aftab, Ahmed, Tanveer   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An Improved 2D Meshfree Radial Point Interpolation Method for Stress Concentration Evaluation of Welded Component

Applied Sciences, 2020
The study of characterizing the stress concentration effects at welds is one of the most important research directions for predicting the fatigue life of welded components.
Fuming Bao, Bingzhi Chen, Yanguang Zhao, Xinglin Guo   +3 more
doaj   +1 more source

Stress concentration factors of multi-planar tubular XT-joints subjected to out-of-plane bending moments

, 2020
The majority of tubular joints commonly found in offshore jacket structures are multi-planar. Investigating the effect of loaded out-of-plane braces on the values of the stress concentration factor (SCF) in offshore tubular joints has been the objective ...
Kouhi, Ahmad, Kouhi, A, Ahmadi, Hamid, Ahmadi, H   +3 more
core   +1 more source