Results 61 to 70 of about 2,696,756 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Ultrasonic Phased Array Inspection Technology for Side Door of Ram BOP Shell

open access: yesShiyou jixie, 2022
Ram BOP is the key equipment of well control and the sealing part of its side door has always been a weak point.Under high pressure impact and cyclic load,stress concentration occurs locally,producing fatigue cracks.In order to effectively detect the ...
Wang Shiqiang   +6 more
doaj  

THE ANALYSIS OF CRACK ON COMPOSITE MATERIALS BY USING ENERGY METHOD [PDF]

open access: yesمجله مدل سازی در مهندسی, 2009
  A . Fereidoon1,*, F . Yektaye Kia2     1- Associate Professor, Faculty of Mechanical Engineering, Semnan University, Semnan, Iran.   2- M.Sc. Student, Faculty of Mechanical Engineering, Semnan university, Semnan, Iran.
عبدالحسین فریدون   +1 more
doaj   +1 more source

Profile of Clients Seeking Consultation at Yoga Therapy Department: A Cross Sectional Study [PDF]

open access: yes, 2010
It is estimated that between 10% and 30% of the general practice population are mentally or emotionally disturbed. Physical complaints, multiple aches and pains are construed as signs and symptoms of stress. Although yoga is considered as beneficial, any
K, Annapoorna, KS, Latha
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Finite Element Analysis on Mechanical Strength of Casing at Slip Hanger in Ultra-deep Wells

open access: yesShiyou jixie, 2023
In order to solve the casing failure occurred at slip clamp of wellhead hanger when lifting the oil production cross for replacing the sealing element in an oilfield in Xinjiang,combined with the ø232.5 mm W type slip hanger used in Well X1,a 3D ...
Lian Zhanghua   +4 more
doaj  

Stress concentration investigations using NASTRAN [PDF]

open access: yes
Parametic investigations are performed using several two dimensional finite element formulations to determine their suitability for use in predicting extremum stresses in marine propellers. Comparisons are made of two NASTRAN elements (CTRIM6 and CTRAIA2)
Gillcrist, M. C., Parnell, L. A.
core   +1 more source

FTIR analysis of aviation fuel deposits [PDF]

open access: yes, 1984
Five modes of operation of the Nicolet 7199 Fourier Transform Infrared Spectrophotometer have been evaluated for application in analysis of the chemical structure of accelerated storage/thermal deposits produced by jet fuels.
Helmick, L. S., Seng, G. T.
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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