Results 71 to 80 of about 924,126 (294)

Exercise is medicine for patients with major depressive disorders : but only if the “pill” is taken!

Neuropsychiatric Disease and Treatment, 2016
Markus Gerber,1 Edith Holsboer-Trachsler,2 Uwe Pühse,3 Serge Brand1,2 1Department of Sport, Exercise and Health, Division of Sport and Psychosocial Health, University of Basel, 2Center for Affective, Stress and Sleep Disorders, Psychiatric ...
Gerber M, Holsboer-Trachsler E, Pühse U, Brand S   +3 more
doaj  

Addressing occupational stress among health staff in non-government controlled Northern Syria: Supporting resilience in a dangerous workplace

Torture, 2018
Introduction: Syrian medical staff working in non-government controlled areas of Syria operate in situations that expose them to great personal danger, while they must often face the same challenges as the people they help.
Mahmood Othman, Zachary Steel, Catalina Lawsin, Ruth Wells   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder

Frontiers in Psychiatry, 2017
ObjectiveBrain imaging studies in patients with post-traumatic stress disorder (PTSD) have implicated a circuitry of brain regions including the medial prefrontal cortex, amygdala, hippocampus, parietal cortex, and insula.
James Douglas Bremner, James Douglas Bremner, James Douglas Bremner, James Douglas Bremner, James Douglas Bremner, Sanskriti Mishra, Carolina Campanella, Majid Shah, Nicole Kasher, Sarah Evans, Negar Fani, Amit Jasvant Shah, Amit Jasvant Shah, Collin Reiff, Lori L. Davis, Lori L. Davis, Lori L. Davis, Viola Vaccarino, Viola Vaccarino, James Carmody   +19 more
doaj   +1 more source

Role of Photobiomodulation Therapy in Modulating Oxidative Stress in Temporomandibular Disorders. A Systematic Review and Meta-Analysis of Human Randomised Controlled Trials [PDF]

, 2021
Reem Hanna, Snehal Dalvi, René‐Jean Bensadoun, Stefano Benedicenti   +3 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Evaluation of Circulating Levels of ICAM-1 in Obstructive Sleep Apnea (OSA) Adults: Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Link Between OSA and Cardiovascular Disease

Life
Obstructive sleep apnea (OSA) is a common condition characterized by repeated airway collapses during sleep, contributing to oxygen desaturation, arousals, and significant cardiovascular complications.
Mohammad Moslem Imani, Arya Imani, Masoud Sadeghi, Annette Beatrix Brühl, Serge Brand   +4 more
doaj   +1 more source

Posttraumatic stress disorder and aggression among post-9/11 veterans: The role of shame

, 2021
Rebecca J. Zakarian, Meghan E. McDevitt‐Murphy   +1 more
openalex   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source