Results 131 to 140 of about 2,700,982 (237)

IL-17 stimulates erythropoiesis in vivo by amplifying the response of erythroid progenitors to erythropoietin.

PLoS Biology
Red blood cell production is regulated by erythropoietin (Epo), maintaining tissue oxygen tension in the steady state and in response to stress. To date, only a handful of factors other than Epo are known to stimulate erythropoiesis, limiting therapeutic
Qiu C Wu, Aishwarya Swaminathan, Ashley Winward, Logan Lalonde, Yung Hwang, Noah Littman, Merav Socolovsky, Allon M Klein   +7 more
doaj   +1 more source

The role of glucocorticoids in erythropoiesis

Frontiers in Hematology
Erythropoiesis is a critical homeostatic process responsible for the production of red blood cells, essential for oxygen delivery to tissues. This review provides a brief overview of erythropoiesis: the maturation of hematopoietic stem cells to ...
Lars L. P. Hanssen, Deena Iskander, Deena Iskander   +2 more
doaj   +1 more source

Tolerability of hormonal treatments in acute hepatic porphyria patients

Internal Medicine Journal, EarlyView.
Abstract Background Acute hepatic porphyria (AHP) flares have been associated with female hormones and the use of hormonal treatments. Women with AHP are traditionally advised to avoid exogenous oestrogen and progesterone, limiting options for contraception and management of menorrhagia, dysmenorrhoea and menopausal symptoms.
Andjela Arandjelovic, Charlotte Ross, Gayle Ross   +2 more
wiley   +1 more source

Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis. [PDF]

Exp Biol Med (Maywood), 2022
Zhang L, Patel S, Soulakova JN, Caldwell CC, St Pierre Schneider B.   +4 more
europepmc   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Distinct stem cell identities converge into shared erythroid stress in ERCC6L2 disease and Shwachman–Diamond syndrome

HemaSphere
ERCC6L2 disease (ED) is a rare bone marrow failure syndrome caused by biallelic germline mutations in ERCC6L2. ED leads to the accumulation of somatic TP53 mutations, myelodysplastic syndrome, and acute myeloid leukemia (AML) with erythroid predominance ...
Laura Langohr, Ilse Kaaja, Suvi P. M. Douglas, Hanna Nebelung, Jessica Koski, Ina Ikonen, Lotta Katainen, Katri Maljanen, Marja Hakkarainen, Tuulia Räisänen, Riitta Niinimäki, Sakari Kakko, Timo Siitonen, Sadiksha Adhikari, Markus Vähä‐Koskela, Caroline A. Heckman, Jenni Lahtela, Ulla Wartiovaara‐Kautto, Esa Pitkänen, Outi Kilpivaara   +19 more
doaj   +1 more source

Loss of STAT1 and Nitric Oxide Signaling Compromises the Development of the Stress Erythropoiesis Niche 2260816

Introduction Steady-state erythropoiesis generates erythrocytes in the bone marrow to replace senescent cells cleared by the spleen.
Robert Paulson, Baiye Ruan, Rajeswaran Mani, Aashka Atul Shah   +3 more
core   +1 more source

Challenging Host Specificity: Malacosporean Parasite Dynamics—Tetracapsuloides bryosalmonae Beyond Salmonids—An Infection Experiment

Journal of Fish Diseases, EarlyView.
ABSTRACT Proliferative Kidney Disease (PKD) is a severe parasitic disease of salmonids caused by the malacosporean endoparasite Tetracapsuloides bryosalmonae. In the fish intermediate host, the parasite is disseminated via the circulatory system and ultimately reaches the kidney, where it matures before releasing infective spores into the environment ...
Céline Möckli, Nicolas Diserens, Gary Delalay, Gastón Moré, Heike Schmidt‐Posthaus   +4 more
wiley   +1 more source

TKI-mediated inhibition of NLRP1 inflammasome restores erythropoiesis in DBA syndrome

EMBO Molecular Medicine
Diamond-Blackfan anemia syndrome (DBAS) is marked by defective erythropoiesis caused by impaired ribosome biogenesis and aberrant signaling. Here, we investigate how ribosomal stress-induced activation of the NLRP1 inflammasome affects erythroid ...
Juan M Lozano-Gil, Lola Rodríguez-Ruiz, Manuel Palacios, Jorge Peral, Susana Navarro, José L Fuster, Cristina Beléndez, Andrés Jérez, Laura Murillo-Sanjuán, Cristina Díaz-de-Heredia, Guzmán López-de-Hontanar, Josune Zubicaray, Julián Sevilla, Francisca Ferrer-Marín, María P Sepulcre, María L Cayuela, Diana García-Moreno, Alicia Martínez-López, Sylwia D Tyrkalska, Victoriano Mulero   +19 more
doaj   +1 more source