Results 171 to 180 of about 1,074,800 (318)
Pulsed magneto-acoustic emission sensor array for stress measurement and material.’characterisation
, 2006 This paper introduces a new method of pulsed magnetic acoustic emission (MAE) for stress detection and material characterisation and investigates the viability of implementing an acoustic emission sensor array for enhanced location information and ...
Tian, Gui Yun, Wilson, J.
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Dual boundary element method for axisymmetric crack analysis
, 2002 In this paper a dual boundary element formulation is developed and applied to the evaluation of stress intensity factors in, and propagation of, axisymmetric cracks.
Wrobel, LC, Lacerda, LA
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Teacher stress among Tawjihi teachers in Jordan and their adopted coping strategies to reduce stress
There has been increasing interest in occupational stress during the last two decades. While studies have been carried out in developed countries, few have been conducted in developing countries, particularly in the field of education.
Alghaswyneh, Sawsan A I
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Thermodynamically Consistent Linear Electroelastic Formulation and FEM Study of Patch-Actuated Smart Structures: Validation and Interface Stress Evaluation. [PDF]
Materials (Basel)Usal MMA, Özer H.
europepmc +1 more source
Oxidative stress evaluation of skeletal muscle in ischemia-reperfusion injury using enhanced magnetic resonance imaging. [PDF]
Sci Rep, 2020 Kuroda Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source