Results 61 to 70 of about 1,074,800 (318)

Naoxintong capsule decreases circulating exosomes of miR-382-5p to protect LPS-induced vascular endothelial cell injury by targeting STC1 in vitro

Frontiers in Pharmacology
BackgroundCardiovascular and cerebrovascular diseases, major health threats in aging populations, involve vascular endothelial injury as a key pathological factor. Circulating exosomes, a type of extracellular vesicles involved in substance transport and
Ziyan Xu, Hao Wu, Weiyang Fan, Fenzhao Meng, Shuangfei Hu, Muhan Zou, Yixuan Chen, Weiwei Su, Peibo Li   +8 more
doaj   +1 more source

Sensory Over-Responsivity as an Added Dimension in ADHD

Frontiers in Integrative Neuroscience, 2019
Years of research have added to our understanding of Attention Deficit Hyperactivity Disorder (ADHD). None-the-less there is still much that is poorly understood.
Shelly J. Lane, Shelly J. Lane, Stacey Reynolds   +2 more
doaj   +1 more source

Evaluation of Oxidative Stress in Ectopic Pregnancies.

Acta bio-medica : Atenei Parmensis, 2022
The aim of the study is to show the relationship between oxidative stress and ectopic pregnancy.A total of 62 patients, 31 in the ectopic pregnancy group (study group) and 31 in the first-trimester pregnancy (control group) were included in the study.
Çakmak, Fatih, Çakmak, Kübra, Topbaş Selçuki, Nura Fitnat, Üreyen Özdemir, Eda, Yalçın Bahat, Pınar, NEŞELİOĞLU, SALİM, EREL, ÖZCAN   +6 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Naringenin Targets PI3K p85alpha to Suppress PI3K/AKT Signaling Pathway and Ameliorate Disordered MMP-9 Secretion in Cigarette Smoke Extract-Induced Alveolar Macrophages In Vitro

Cells
Background: Naringenin has demonstrated potential therapeutic effects against cigarette smoke-induced lung injury; however, its underlying mechanisms of regulating matrix metalloproteinase-9 (MMP-9) in alveolar macrophages remain unclear.
Weiyang Fan, Ziyan Xu, Mengli Zhong, Xiao Wu, Pan Chen, Zhen Chen, Weiwei Su, Hao Wu, Peibo Li   +8 more
doaj   +1 more source

An Optimization Method of Precision Assembly Process Based on the Relative Entropy Evaluation of the Stress Distribution

Entropy, 2020
The entropy evaluation method of assembly stress has become a hot topic in recent years. However, the current research can only evaluate the maximum stress magnitude and stress magnitude uniformity, and it cannot evaluate the stress position distribution.
Zifu Wang, Zhijing Zhang, Xiao Chen, Xin Jin   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Evaluation of salivary cortisol as a biomarker of self-reported mental stress in field studies

, 2004
This study examine's the association between self-reported mental stress and the salivary cortisol response via a systematic literature review by using recommendations from the Cochrane Collaboration.
Hansen, AM, Örbaek, Palle,, Hjortskov, N, Örbaek, Palle, Lund University., Garde, AH   +5 more
core   +1 more source

An integrated approach to the determination and consequences of residual stress on the fatigue performance of welded aircraft structures [PDF]

, 2005
Although residual stress in welded structures and components has long been known to have an effect on their fatigue performance, access to reliable, spatially accurate residual stress field data has been limited.
Edwards, Lyndon, Fitzpatrick, Michael E., Yapp D, Yapp, D, Sinclair, I, Fitzpatrick, M. E., Sinclair, I., Edwards L, Sinclair I, Edwards, L, Zhang, X, Zhang, Xiang, Irving, P. E., Irving, Phil E., Fitzpatrick M E, Fitzpatrick ME, Irving PE, Zhang X, Irving P E, Yapp, David   +19 more
core   +1 more source

Illegitimate work tasks: an investigation of psychometric properties of the Swedish version of the BITS instrument and its suitability in human versus ‘non-human’ service occupations

BMC Public Health
Background Illegitimate tasks, i.e. working tasks that are perceived as unnecessary or unreasonable, are commonly measured by the Bern Illegitimate Tasks Scale (BITS).
Johanna Stengård, Constanze Leineweber, Hanne Berthelsen   +2 more
doaj   +1 more source