Results 61 to 70 of about 12,129,309 (293)

Analysis of dynamics variation against thixotropic parameter’s preferential range [PDF]

open access: yesTheoretical and Applied Mechanics, 2018
Variation in the dynamics of a steady-state blood flow through a stenosed tapered artery has been investigated corresponding to changes in thixotropic parameter λ over the range [0,1].
Shahid Nazish
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Adverse-Pressure-Gradient effects on Turbulent Boundary Layers [PDF]

open access: yes, 2018
Wall-bounded turbulence is present in many relevant fluid-flow problems such as the flow around wings, land and sea vehicles, or in turbines, compressors, etc. Simplified scenarios, such as the zero-pressure-gradient (ZPG) turbulent boundary layers (TBL)
Discetti, Stefano
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Evaluating the fatigue life of notched components based on the stress gradient model with variable support effects

open access: yesMaterials & Design
As the notch location of engineered components suffers from size effect, thereby making it difficult to accurately predict the fatigue life of engineered components.
Zhuo Zhou   +3 more
doaj   +1 more source

Deflections and curvatures of a film-substrate structure with the presence of gradient stress in MEMS applications [PDF]

open access: yes, 2007
The close form solutions of deflections and curvatures for a film-substrate composite structure with the presence of gradient stress are derived. With the definition of more precise kinematic assumption, the effect of axial loading due to residual ...
张吟   +1 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Constraint Effects on the Elastic-Plastic Fracture Behaviour in Strain Gradient Solids

open access: yes, 2002
Crack-tip constraint effects (or T-stress effects) on the elastic-plastic fracture behaviour in strain gradient materials are analysed in the present study.
魏悦广   +1 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy