Results 271 to 280 of about 4,657,064 (329)

Proteasome inhibition by VR23 enhances autophagic clearance of FUS^P525L-mediated persistent stress granule in SH-SY5Y cells. [PDF]

Mol Brain
Kim SH, So JH, Kim YH, Kim HS, Park NY, Kim JB, Jo DS, Yeom E, Lee JA, Bae JE, Cho DH.   +10 more
europepmc   +1 more source

Toward the harmonization of bioequivalence guidelines in Europe: Commentary on the state of the art and future priorities under ICH M13A for immediate‐release oral forms

British Journal of Clinical Pharmacology, EarlyView.
Domenico Nocera, Giusi Forastiero, Andrea Logreco, Alessia Proietti, Antonio Galluccio, Carlotta Lunghi, Elisabetta Poluzzi, Fabrizio De Ponti   +7 more
wiley   +1 more source

Protein‐Independent Liquid–Liquid Phase Separation of Adenosine Triphosphate Under Crowded Conditions

Chemistry – A European Journal, EarlyView.
ATP itself is able to undergo liquid–liquid phase separation in the presence of the macromolecular crowding agent PEG and physiological ATP concentrations are sufficient for phase separation in the presence of mM Mg2+ and crowders, mimicking intracellular conditions.
Robert Dec, Wojciech Dzwolak, Roland Winter   +2 more
wiley   +1 more source

UBAP2L-driven stress granule formation links oxaliplatin resistance to gastric cancer. [PDF]

Commun Biol
Wu C, Yan Y, Chen Q, Lian Z, He J, Ling R, Lei X, Peng Y, Zheng B, Yang Q, Ye G, Ma W, Li G.   +12 more
europepmc   +1 more source

Economic and environmental implications of the development of UASB reactors in Mexico for sustainable industrial wastewater treatment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The objective of this work is to demonstrate that the inclusion of an up‐flow anaerobic sludge bed (UASB reactor) within an industrial wastewater treatment plant reduces the plant's investment and operating costs compared to a system based solely on conventional complete‐mix activated sludge (CMAS), operating under the same design principles ...
Juan Manuel Morgan‐Sagastume, Adalberto Noyola   +1 more
wiley   +1 more source

Stress granule-mediated ZBP1 activation drives necroptotic cell death in non-obstructive azoospermia and testicular aging. [PDF]

Proc Natl Acad Sci U S A
Lei H, Li D, Chen J, Du B, Jiang K, Xu T, Han H, Fan W, Tian L, Wang X.   +9 more
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

O-GlcNAcylation of UBAP2L regulates stress granule formation and sunitinib resistance in clear cell renal cell carcinoma. [PDF]

J Exp Clin Cancer Res
Xing J, Li B, Wang S, Wang Z, Miao C.
europepmc   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia-Induced Stress Granule Formation. [PDF]

Adv Sci (Weinh)
Li C, Liu Z, Zhu L, Wu G, Fu C, Li H, He T, Shen M, Liu H.   +8 more
europepmc   +1 more source