Results 251 to 260 of about 4,657,064 (329)

PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins

Cell Research, 2019
Yongjia Duan, Aiying Du, Jinge Gu, Gang Duan, Chen Wang, X. Gui, Zhiwei Ma, Beituo Qian, Xue Deng, Kai Zhang, Le Sun, Kuili Tian, Yaoyang Zhang, Hong Jiang, Cong Liu, Yanshan Fang   +15 more
semanticscholar   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan, E. Svaluto‐Ferro, N. Kovalska, G. Graeber, F. Vagliani, D. Basso, A. Turconi, M. Makowska, G. Blugan, C. Battaglia, M. V. F. Heinz   +10 more
wiley   +1 more source

Stress granule dynamics orchestrate colitis-to-cancer transition via TOM1-mediated disassembly and driven oncogenesis in response to inflammatory oxidative stress. [PDF]

Redox Biol
Wan Z, Qian M, Yu J, Shu T, Wang D, Liang X, Chen R, Shi B, Cui H, Chen Z, Jiang J.   +10 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

A stress granule-associated RNA-binding protein FAM120A drives cisplatin resistance in non-small cell lung cancer. [PDF]

J Biochem
Hayai S, Suzuki MM, Iijima K, Shinjo K, Murofushi Y, Xie J, Nishimura T, Ishii M, Kondo Y.   +8 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Connecting the Dots: Stress Granule and Cardiovascular Diseases. [PDF]

J Cardiovasc Transl Res
Yang G, Wang Y, Guo J, Rui T.
europepmc   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source