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FAM98A is localized to stress granules and associates with multiple stress granule-localized proteinsopenaire
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Autophagy, 2023
Eukaryotic stress granules (SGs) are highly dynamic assemblies of untranslated mRNAs and proteins that form through liquid-liquid phase separation (LLPS) under cellular stress.
Cuiwei Yang +6 more
semanticscholar +1 more source
Eukaryotic stress granules (SGs) are highly dynamic assemblies of untranslated mRNAs and proteins that form through liquid-liquid phase separation (LLPS) under cellular stress.
Cuiwei Yang +6 more
semanticscholar +1 more source
Stress granules: regulators or by‐products?
The FEBS Journal, 2021Cells have to deal with conditions that can cause damage to biomolecules and eventually cell death. To protect against these adverse conditions and promote recovery, cells undergo dramatic changes upon exposure to stress. This involves activation of signaling pathways, cell cycle arrest, translational reprogramming, and reorganization of the cytoplasm.
Daniel Mateju, Jeffrey A. Chao
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Yeast stress granules at a glance
Yeast, 2021AbstractThe formation of stress granules (SGs), membrane‐less organelles that are composed of mainly messenger ribonucleoprotein assemblies, is the result of a conserved evolutionary strategy to cellular stress. During their formation, which is triggered by robust environmental stress, SGs sequester translationally inactive mRNA molecules, which are ...
Tomas Grousl +3 more
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Science Signaling, 2023
Ruptures in lysosomal membranes stimulate the formation of stress granules that plug the holes to enable repair.
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Ruptures in lysosomal membranes stimulate the formation of stress granules that plug the holes to enable repair.
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μMap proximity labeling in living cells reveals stress granule disassembly mechanisms
Nature Chemical BiologyPhase-separated condensates are membrane-less intracellular structures comprising dynamic protein interactions that organize essential biological processes. Understanding the composition and dynamics of these organelles advances our knowledge of cellular
C. Pan +3 more
semanticscholar +1 more source
Stress granule and P-body clearance: Seeking coherence in acts of disappearance.
Seminars in Cell and Developmental BiologyStress granules and P-bodies are conserved cytoplasmic biomolecular condensates whose assembly and composition are well documented, but whose clearance mechanisms remain controversial or poorly described. Such understanding could provide new insight into
J. Buchan
semanticscholar +1 more source
A Narrative Review on Stress Granules and Ultraviolet Stress Granules
Photobiomodulation, Photomedicine, and Laser SurgeryBackground: Stress granules (SGs) are membraneless structures formed through liquid–liquid phase separation in response to cellular stress. These dynamic assemblies play a pivotal role in cellular adaptation and recovery from external stressors by modulating protein synthesis and preserving mRNA integrity ...
Yuru, Cheng +3 more
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Regulation of stress granule formation in human oligodendrocytes
Nature CommunicationsOligodendrocyte (OL) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (MS). Stress granules (SGs) are membrane-less organelles containing mRNAs stalled in translation and considered as participants of the cellular response to ...
Florian Pernin +15 more
semanticscholar +1 more source
Molecular and Cellular Biochemistry, 2018
Stress granules are evolutionally conserved ribonucleoprotein structures that are formed in response to various stress stimuli. Recent studies have demonstrated that proteins with low complexity (LC) regions play a critical role for the formation of stress granules.
Kanako Ozeki +5 more
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Stress granules are evolutionally conserved ribonucleoprotein structures that are formed in response to various stress stimuli. Recent studies have demonstrated that proteins with low complexity (LC) regions play a critical role for the formation of stress granules.
Kanako Ozeki +5 more
openaire +2 more sources