Results 71 to 80 of about 2,717,503 (245)

Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory

, 2018
Stress-associated mental disorders and diabetes pose an enormous socio-economic burden. Glucose dysregulation occurs with both psychosocial and metabolic stress.
Treccani, Giulia, Hasch, Annika, van der Kooij, Michael, Müller, Marianne B., Miederer, Isabelle, Voelxen, Nadine, Walenta, Stefan, Jene, Tanja   +7 more
core   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

The measurement of plasma fructosamine as a diagnostic tool to improve the interpretation of plasma glucose and proteins in alpacas (Vicugna pacos)

Scientific Reports
This study assesses the use of fructosamine as a diagnostic tool for hyperglycemia in alpacas in view of their sensitivity to stress and susceptibility to conditions like lipid mobilization syndrome.
Frederik Kiene, Johannes Buchallik-Schregel, Petra Röhrig, Saskia Neubert, Alexandra von Altrock, Benjamin U. Bauer, Thies J. Nicolaisen, Marion Schmicke, Martin Ganter, Matthias Gerhard Wagener   +9 more
doaj   +1 more source

Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases

Общая реаниматология, 2013
Critically ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction.
A. V. Nikolenko, I. N. Prelous, I. N. Leiderman   +2 more
doaj   +1 more source

BLOOD GLUCOSE LEVEL AND STRESS HYPERGLYCEMIA IN ACUTE ISCHEMIC STROKE [PDF]

, 2017
Objective: To determine the frequency of stress hyperglycemia and estimate the blood sugar level in patients with acute ischemic stroke. Patients and Methods: This cross sectional study of six months was conducted at tertiary care hospital Hyderabad. All
Khuda Bux Mangrio *, Dr. Rafi Ahmed Ghori , Dr. Naveed Aslam Lashari , Dr. Hamid Nawaz Ali Memon , Dr. Umair Ahmed Ghori , Dr. Sumera Bukhari and Dr. Zulfiqar Ali Qutrio Baloch
core   +1 more source

The stress hyperglycemia in comatose patients

Pain, anesthesia and intensive care, 2016
Мета дослідження – аналіз динаміки стресової  гіперглікемії у коматозних пацієнтів на тлі інсульту.Матеріали та методи. Проспективне дослідження включало 100 пацієнтів з гострим порушенням мозкового кровообігу з оцінкою за шкалою ком Глазго (ШКГ) 5–8 балів.
openaire   +4 more sources

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

The Stress Hyperglycemia Ratio is Associated with Hemorrhagic Transformation in Patients with Acute Ischemic Stroke

Clinical Interventions in Aging, 2021
Chengxiang Yuan,1,* Siyan Chen,1,* Yiting Ruan,1 Yuntao Liu,1 Haoran Cheng,1 Yaying Zeng,1 Yunbin Chen,1 Qianqian Cheng,2 Guiqian Huang,1 Weilei He,1 Jincai He1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University ...
Yuan C, Chen S, Ruan Y, Liu Y, Cheng H, Zeng Y, Chen Y, Cheng Q, Huang G, He W, He J   +10 more
doaj  

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source