Results 181 to 190 of about 5,412,654 (273)

Immunomodulatory, Antibacterial, Antioxidative and EGF‐Delivering Hydrogel Remodels Wound Microenvironment for Infected Diabetic Wound Healing

open access: yesNational Materials, EarlyView.
In this study, we engineered an antibacterial, antioxidative and epidermal grow factor‐encapsulated multifunctional hydrogel for the repair of chronic and refractory wounds. The hydrogel markedly promoted wound healing in rat models of diabetic foot ulcers and infected wounds by modulating wound microenvironment.
Zheng Zou   +5 more
wiley   +1 more source

Outpatient preoperative parenteral nutrition in malnourished surgical patients: A feasibility study (the OPPORTUNITY study)

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley   +1 more source

Effect of GLP‐1 receptor agonist on nutrient intake: A narrative review

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Humans have a primitive defense mechanism called metabolic adaptation that slows voluntary weight loss. It works by downregulating hormones that reduce food intake and by lowering the metabolic rate. Second‐generation GLP‐1 receptor agonists, such as semaglutide or tirzepatide, promote weight loss by targeting this hormonal system to control ...
Ken Fujioka
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

open access: yesObesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter   +14 more
wiley   +1 more source

Divergent Obesity Classification Between the Edmonton Obesity Staging System and the Lancet Commission Model

open access: yesObesity, EarlyView.
ABSTRACT Objective BMI alone does not capture obesity‐related health heterogeneity. The Edmonton Obesity Staging System (EOSS) grades obesity severity based on comorbidities and functional impairment, whereas the Lancet Commission Diagnostic Model for Obesity (DMO) distinguishes preclinical from clinical obesity based on organ dysfunction.
Tobias Hagemann   +3 more
wiley   +1 more source

Association between stress hyperglycemia ratio and 72-hour delirium in critically ill patients: A retrospective cohort study from the MIMIC-IV database. [PDF]

open access: yesMetabol Open
Huang H   +19 more
europepmc   +1 more source

Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population‐Based Healthcare Database

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To estimate Bell's palsy incidence and evaluate the prevalence and associations with diabetes and other cardiometabolic conditions. Study Design Population‐based cohort study. Setting Clalit Health Services, the largest healthcare provider organization in Israel (2005‐2022).
Tomer Boldes   +5 more
wiley   +1 more source

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