Results 61 to 70 of about 778,674 (264)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Modeling of a cyclic shell with a local deepening on the inner surface
Учёные записки Казанского университета: Серия Физико-математические наукиA mathematical model for calculating the stress-strain state (SSS) of a cyclic shell with a defect in the form of a local non-through depression on the inner surface was constructed using a three dimensional spline version of the finite element method ...
S. N. Yakupov +3 more
doaj +1 more source
Development of strain gages to analyze the stress intensity factor of a crack tip
Nihon Kikai Gakkai ronbunshu, 2015 There are currently one or two kinds of strain gages to measure the stress intensity factor. It might not be sometimes easy to analyze the stress intensity factor with those gages.
Shigeru KUROSAKI +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Journal of Mechanical EngineeringThe paper is devoted to the study of temperature and stress distribution in the medium-pressure rotor of the K-200-130 turbine, which are of considerable interest when predicting the durability of this equipment and extending its operation beyond the ...
Serhii R. Lishchuk, Vitalii A. Peshko
doaj +1 more source
Shock and Vibration, 2019 To analyze the effect of the width of a prefabricated crack on the dimensionless stress intensity factor of notched semi-circular bend (NSCB) specimens, ABAQUS software was employed to perform numerical calibration of the crack tip stress intensity ...
Sheng Zhang, Longfei Wang, Mingzhong Gao
doaj +1 more source
Nihon Kikai Gakkai ronbunshu, 2016 Crack opening displacement around a mode I surface crack tip was measured by digital image correlation method to determine the stress intensity factor and the effective stress intensity factor range.
Yuichi ONO +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On the Constitutive Equation of a Low Carbon Steel
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2008 The paper shows the results of the researches concerning the equation of deformation behavior of low carbon steel. The behavior law is established starting from the experimental torsion moment.
Nicolae CANANAU +3 more
doaj
Threshold intensity factors as lower boundaries for crack propagation in ceramics
BioMedical Engineering OnLine, 2004 Background Slow crack growth can be described in a v (crack velocity) versus KI (stress intensity factor) diagram. Slow crack growth in ceramics is attributed to corrosion assisted stress at the crack tip or at any pre-existing defect in the ceramic. The
Walter Per-Ole +2 more
doaj +1 more source