Results 111 to 120 of about 1,542,365 (380)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Threshold intensity factors as lower boundaries for crack propagation in ceramics
BioMedical Engineering OnLine, 2004 Background Slow crack growth can be described in a v (crack velocity) versus KI (stress intensity factor) diagram. Slow crack growth in ceramics is attributed to corrosion assisted stress at the crack tip or at any pre-existing defect in the ceramic. The
Walter Per-Ole +2 more
doaj +1 more source
Notch Effects on the Stress Intensity Factor and on the Fatigue Crack Path for Eccentric Circular Internal Cracks in Elliptically Notched Round Bars under Tensile Loading. [PDF]
Materials (Basel), 2022 Toribio J +3 more
europepmc +1 more source
Stress-intensity factor equations for cracks in three-dimensional finite bodies [PDF]
Empirical stress intensity factor equations are presented for embedded elliptical cracks, semi-elliptical surface cracks, quarter-elliptical corner cracks, semi-elliptical surface cracks at a hole, and quarter-elliptical corner cracks at a hole in finite
Newman, J. C., Jr., Raju, I. S.
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Approximate determination of stress intensity factor for multiple surface cracks [PDF]
FME Transactions, 2018 In this paper a versatile and easy to use approximate procedure was used for the estimation of mode I stress intensity factors in case of multiple surface cracks in a three dimensional elastic body, subjected to remote uniaxial tensile loading.
Kastratović Gordana +3 more
doaj
Influence of Stress Intensity Factor on Rail Fatigue Crack Propagation by Finite Element Method. [PDF]
Materials (Basel), 2021 Gao R, Liu M, Wang B, Wang Y, Shao W.
europepmc +1 more source
Fatigue crack growth in unidirectional metal matrix composite [PDF]
The weight function method was used to determine the effective stress intensity factor and the crack opening profile for a fatigue tested composite which exhibited fiber bridging. The bridging mechanism was modeled using two approaches; the crack closure
Ghosn, Louis J. +2 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Stress Intensity Factor for Aluminum and Copper Spot Weld Joints
Journal of Applied Science and EngineeringFor decades, resistance spot welding (RSW) between aluminum and copper has encountered difficulties; however, it remains essential for modern applications.
Marwah Sabah Fakhri +2 more
doaj +1 more source