Results 31 to 40 of about 1,542,365 (380)

A Simplified Evaluation Method of the Stress Intensity Factor of a Circumferential Crack in a Cylinder Subjected to Axisymmetric Loads [PDF]

open access: yes, 1997
A simplified method to approximately evaluate the stress intensity factor of an arbitrarily located circumferential crack in a cylinder subjected to axisymmetric loads was theoretically derived, based on the theory of cylindrical shell and compliance ...
飯井, 俊行, 渡邊, 勝彦
core   +2 more sources

Numerical Simulation of the Influence of Width of a Prefabricated Crack on the Dimensionless Stress Intensity Factor of Notched Semi-Circular Bend Specimens

open access: yesShock and Vibration, 2019
To analyze the effect of the width of a prefabricated crack on the dimensionless stress intensity factor of notched semi-circular bend (NSCB) specimens, ABAQUS software was employed to perform numerical calibration of the crack tip stress intensity ...
Sheng Zhang, Longfei Wang, Mingzhong Gao
doaj   +1 more source

Two objective and independent fracture parameters for interface cracks and a paradox [PDF]

open access: yes, 2016
Due to the oscillatory singular stress field around a crack tip, interface fracture has some peculiar features. This paper is focused on two of them. One can be reflected by a proposed paradox that geometrically similar structures with interface cracks under similar loadings may have different failure behaviors.
arxiv   +1 more source

Determining stress intensity factor in bending reinforced Concrete beams

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
There has been analytically solved the problem of determining the stress state in the cross section of bending reinforced concrete beams with a crack in a linear formulation.
О. Khabidolda   +3 more
doaj   +1 more source

Stress Distributions and Notch Stress Intensity Factors in Multimaterial V-notches Under Antiplane Shear and Torsion [PDF]

open access: yesarXiv, 2021
This study investigates how the insertion of multimaterial circular regions embracing the tip of a finite V-notch can be used to reduce the Notch Stress Intensity Factors (NSIFs) in structures subjected to antiplane shear or torsion. Towards this goal, this work presents a novel theoretical framework to calculate stress distributions and NSIFs in ...
arxiv  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Mode I stress intensity factor with various crack types

open access: yesFracture and Structural Integrity, 2021
Presence of cracks in mechanical components needs much attention, where the stress field is affected by cracks and the propagation of cracks may be occurred causing the damage.
Ehab Samir Mohamed Mohamed Soliman
doaj  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Wave diffraction by a line of finite crack in a saturated two-phase medium [PDF]

open access: yes, 2013
An application of the Biot’s theory to the diffraction problem of plane harmonic dilatational waves (P-waves) of the first kind and the second kind by a line crack or geometric discontinuity of finite width embedded in a saturated two-phase medium is ...
Phurkhao, P.
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

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