Results 41 to 50 of about 1,447,308 (304)

STRESS INTENSITY FACTOR IN MATRIX-AGGREGATE CONTACT ZONE

open access: yesНаука и техника, 2010
The presented approach and illustrative problems clearly demonstrate significant possibilities of destruction mechanics in development of the finished theory on frost concrete and reinforced concrete destruction which is based on peculiar features of ...
S. N. Leonovich
doaj  

Effect of gradient of stress intensity factor at a crack tip on fatigue crack growth and correction method for the effect

open access: yesNihon Kikai Gakkai ronbunshu, 2014
The stress intensity factor can be applied as an evaluation parameter of crack growth under small-scale yielding conditions. Moreover, the stress intensity factor corrected by the plastic zone correction can potentially be used as an evaluation parameter
Sho KAWATSU   +4 more
doaj   +1 more source

The Griffith Crack and the Interaction between Screw Dislocation and Semi-Infinite Crack in Cubic Quasicrystal Piezoelectric Materials

open access: yesCrystals, 2022
The Griffith crack problem and the interaction between screw dislocation and semi-infinite crack in cubic quasicrystal piezoelectric materials are studied by using the complex variable function method.
Jiandong Pi, Lianhe Li
doaj   +1 more source

Criticality of porosity defects on the fatigue performance of wire + arc additive manufactured titanium alloy [PDF]

open access: yes, 2019
This study was aimed at investigating the effect of internal porosity on the fatigue strength of wire + arc additive manufactured titanium alloy (WAAM Ti-6Al-4V).
Awd, Mustafa   +6 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Stress Intensity Factors - T-Stresses - Weight Functions

open access: yes, 2008
Failure of cracked components is governed by the stresses in the vicinity of the crack tip. The singular stress contribution is characterised by the stress intensity factor K, the first regular stress term is represented by the so-called T-stress. Sufficient information about the stress state is available, if these two parameters are known Results for ...
openaire   +5 more sources

A new formulation for estimating maximum stress intensity factor at the mid plane of a SENB specimen: Study based on 3D FEA

open access: yesFracture and Structural Integrity, 2014
In this investigation, three-dimensional elastic finite element analyses have been conducted to compute the stress intensity factor (KI) in a SENB specimen with varied thickness (B) and crack-length to width ratio (a/W).
S. K. Kudari, K. G. Kodancha
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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