Results 51 to 60 of about 588,944 (311)

Relationship Between Stress, its Management and Public Well-being in Lithuania: Effect of Sociodemographic and Clinical Factors

Social Welfare: Interdisciplinary Approach
The aim of the study was to assess the individual stress intensity and its management in Lithuania in the context of public well-being, concentrating on the effects of socio-demographic and clinical factors on stress intensity.
Lolita Rapolienė, Diana Šaparnienė, Arvydas Martinkėnas, Inga Dailidienė, Aelita Bredelytė, Gintarė Grigaliūnaitė, Dovydas Rapolis   +6 more
doaj   +1 more source

Adaptive Finite Element Prediction of Fatigue Life and Crack Path in 2D Structural Components

Metals, 2020
The existence of a hole near a growing fatigue crack can cause the crack trajectory to deviate. Unless the hole is too close to the crack, the crack is arrested at the edge of the hole and does not progress further.
Abdullateef H. Bashiri, Abdulnaser M. Alshoaibi   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Local approaches for the fracture assessment of notched components: the research work developed by Professor Paolo Lazzarin

Fracture and Structural Integrity, 2015
Brittle failure of components weakened by cracks or sharp and blunt V-notches is a topic of active and continuous research. It is attractive for all researchers who face the problem of fracture of materials under different loading conditions and deals ...
F. Berto
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Fundamental Solutions for the Stress Intensity Factors of Modes I, II And III. The Axially Symmetric Problem

, 2015
The subject of the paper are Green’s functions for the stress intensity factors of modes I, II and III. Green’s functions are defined as a solution to the problem of an elastic, transversely isotropic solid with a penny-shaped or an external crack under ...
B. Rogowski, Rogowski, B.
core   +1 more source

Transient Stress Intensity Factors of Functionally Graded Hollow Cylinders with Internal Circumferential Cracks

Latin American Journal of Solids and Structures
In this paper, transient thermomechanical stress intensity factors for functionally graded cylinders with complete internal circumferential cracks are obtained using the weight function method.
Iman Eshraghi, Nasser Soltani, Mohammad Rajabi   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Elastodynamic stress-intensity factors for a semiinfinite crack under 3-d combined mode loading

, 1995
The dynamic stress intensity factor histories for a half plane crack in an otherwise unbounded elastic body are analyzed. The crack is subjected to a traction distribution consisting of two pairs of suddenly-applied shear point loads, at a distance L ...
Tu LC, Ping LX, PING, LX (reprint author), ACAD SINICA,INST MECH,BEIJING 100080,PEOPLES R CHINA.   +2 more
core   +1 more source

Work stress, smoking status and smoking intensity: an observational study of 46 190 employees [PDF]

, 2005
Study objective: To examine the relationship between work stress, as indicated by the job strain model and the effort-reward imbalance model, and smoking. Setting: Ten municipalities and 21 hospitals in Finland.
Kivimäki, M, Vahtera, Jussi, Kivimäki, Mika, Kouvonen, Anne, Pentti, Jaana, Virtanen, M, Virtanen, Marianna, Pentti, J, Vahtera, J, Kivimaki, M., Virtanen, M., Kivim�ki, Mika, Vahtera, J., Kouvonen, A, Pentti, J.   +14 more
core   +1 more source