Results 71 to 80 of about 588,944 (311)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2007 For an anti-plane problem, the differential operator is self-adjoint and the corresponding eigenfunctions belong to the Hilbert space. The orthogonal property between eigenfunctions (or between the derivatives of eigenfunctions) of anti-plane problem is ...
徐永君 +2 more
core +1 more source
Stress intensity factor threshold in dental porcelains
Journal of Materials Science: Materials in Medicine, 2007 The stress intensity factor threshold (KI0) is related to the stress level at which cracks start to grow stably, causing the weakening of porcelain prostheses during their use. The values of KI0 of seven dental porcelains (with and without reinforcing leucite crystal, KAlSi2O6) stored in air (22 degrees C, 60% relative humidity) and artificial saliva ...
Humberto Naoyuki, Yoshimura +3 more
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Computation of stress intensity factors by the sub-region mixed finite element method of lines
, 2007 Based on the sub-region generalized variational principle, a sub-region mixed version of the newly-developed semi-analytical 'finite element method of lines' (FEMOL) is proposed in this paper for accurate and efficient computation of stress intensity ...
袁驷 +3 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Enrichment of the Boundary Element Method through the Partition of Unity Method for Fracture Analysis using Local and Global Formulations [PDF]
, 2010 The present thesis proposes an innovative technique of applying enrichment to the Boundary Element Method to allow accurate analysis of 2D crack problems. An overview of fracture mechanics is given, with particular emphasis given to numerical methods and
SIMPSON, ROBERT
core
Evaluation of the intrinsic crack growth rates of weld joints [PDF]
, 2011 A method is presented for evaluating weld intrinsic fatigue crack growth rate (FCGR) by excluding the influence of residual stresses. The method is potentially useful for predicting crack growth lives of structural components using measured FCGR data ...
Xiang Zhang +3 more
core +1 more source
Latin American Journal of Solids and StructuresThe analysis of cracked brittle mechanical components considering linear elastic fracture mechanics is usually reduced to the evaluation of stress intensity factors (SIFs).
Marco Gonzalez +3 more
doaj +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 This paper deals with the effect of adhesion layer on the stress intensity factor for small edge interface crack in bonded plates under uniaxial tension or bending.
Kazuhiro ODA +3 more
doaj +1 more source