Results 91 to 100 of about 3,012,345 (281)

Organizational stressors associated with job stress and burnout in correctional officers: a systematic review. [PDF]

, 2013
BackgroundIn adult correctional facilities, correctional officers (COs) are responsible for the safety and security of the facility in addition to aiding in offender rehabilitation and preventing recidivism.
Bonato, Sarah, Dewa, Carolyn S, Finney, Caitlin, Hensel, Jennifer, Stergiopoulos, Erene   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Synergistic potential of deficit irrigation and grafted eggplant on wild rootstocks for enhanced growth, yield, and water productivity

Applied Water Science
As climate change intensifies water scarcity, sustainable strategies are essential for vegetable production under water-limited conditions. This study evaluates the potential of grafted eggplant onto wild rootstocks under deficit irrigation (DI) to ...
Pratapsingh S. Khapte, Lahu S. Chavan, Sushil S. Changan, Goraksha C. Wakchaure, Raghwendra A. Patil, Lalu Prasad Yadav, T. H. Singh, K. Sammi Reddy   +7 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

STRESS AT THE WORK IN ROMANIAN BANKING SISTEM [PDF]

In a period when the banks are struggling to survive we can realize that stress management becomes a problem. Stress at work can bring real business problems, management and labor productivity can be seriously affected and the level of motivation and ...
Breje Cristina
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Biomass Estimation of mahogany (Swietenia macrophylla): An optimized weighted ensemble-based machine learning approach

Smart Agricultural Technology
Accurate biomass estimation is crucial for assessing tree plantation health, productivity, and carbon dynamics, which underpin not only ecosystem service valuation but also carbon management.
Nobin Chandra Paul, SB Chavan, Shubham Gurav, Navyasree Ponnaganti, Amrut S Morade, VD Kakade, Nilesh Jorvekar, K Ravi Kumar, VN Salunkhe, AR Uthappa, K․Sammi Reddy   +10 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Dragon fruit cultivation in new areas: challenges, management strategies, and insights from India

Discover Agriculture
Dragon fruit is a highly nutritious fruit known for its ability to thrive in diverse soil and climate conditions worldwide, including India. While possessing considerable cultivation potential, dragon fruit yields in India, typically ranging from 15 to ...
V. D. Kakade, A. S. Morade, V. N. Salunkhe, K. M. Boraiah, Dinesh Jinger, Gaurav Singh, S. B. Chavan, Raj Kumar, Aliza Pradhan, Sonal Jadhav, Sachin Magar, Amol Patil, Akash Doke, Priyanka Jadhav, D. D. Nangare, K. Sammi Reddy   +15 more
doaj   +1 more source