Results 91 to 100 of about 3,031,452 (301)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Synergistic potential of deficit irrigation and grafted eggplant on wild rootstocks for enhanced growth, yield, and water productivity

open access: yesApplied Water Science
As climate change intensifies water scarcity, sustainable strategies are essential for vegetable production under water-limited conditions. This study evaluates the potential of grafted eggplant onto wild rootstocks under deficit irrigation (DI) to ...
Pratapsingh S. Khapte   +7 more
doaj   +1 more source

Optimizing sowing time and weather conditions for enhanced growth and seed yield of chia (Salvia hispanica L.) in semi-arid regions [PDF]

open access: yesPeerJ
Background Climate influenced weather events, especially during the flowering, grain filling, and maturity stages, can adversely influence crop yield and quality.
CB Harisha   +12 more
doaj   +2 more sources

Incorporating climate change into pest risk models for forest pathogens : a role for cold stress in an era of global warming? [PDF]

open access: yes, 2013
Climate change may alter the distribution and activity of native and alien pathogens that infect trees and, in severe cases, cause tree death. In this study, potential future changes in climate suitability are investigated for three forest pathogens that
Venette, Robert C.
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Beyond California: States in Fiscal Peril [PDF]

open access: yes, 2009
Analyzes the causes of fiscal stress in nine states facing issues similar to California's: high foreclosure rates, increasing joblessness, loss of state revenues, large budget gaps, legal obstacles to balanced budgets, and poor money management ...
Daniel C. Vock   +5 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Mitigating combined toxic effects of arsenic, ammonia, and high temperature through dietary Iron in fish

open access: yesFrontiers in Immunology
BackgroundThe sustainability of aquaculture is increasingly threatened by major challenges such as aquatic pollution, excessive water abstraction, and climate change.
Neeraj Kumar   +2 more
doaj   +1 more source

Mentes Positivas en Acción: Feasibility Study of a Promotor-Delivered Cognitive Behavioral Stress Management Program for Low-Income Spanish-Speaking Latinas. [PDF]

open access: yes, 2019
Purpose: Low-income Latino immigrants lack access to mental health providers. We explored the feasibility of training promotores to deliver a stress management program in community settings.
Gregorich, Steven   +3 more
core  

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