Results 71 to 80 of about 898,469 (266)

Optimizing sowing time and weather conditions for enhanced growth and seed yield of chia (Salvia hispanica L.) in semi-arid regions [PDF]

open access: yesPeerJ
Background Climate influenced weather events, especially during the flowering, grain filling, and maturity stages, can adversely influence crop yield and quality.
CB Harisha   +12 more
doaj   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Mitigating combined toxic effects of arsenic, ammonia, and high temperature through dietary Iron in fish

open access: yesFrontiers in Immunology
BackgroundThe sustainability of aquaculture is increasingly threatened by major challenges such as aquatic pollution, excessive water abstraction, and climate change.
Neeraj Kumar   +2 more
doaj   +1 more source

Stress Management: Preventing Stress Through Lifestyle Management

open access: yesEDIS, 1969
In today's world, most of us can't avoid stress. We can learn ways to take care of ourselves so stress does notbecome a problem. Taking care of yourself is the first step in stress management. This fact sheet highlights some basic lifestyle practices that keep you healthy and strong so you can prevent stress.
Suzanna Smith, Joe Pergola
openaire   +5 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Multi-trait stability selection drives genetic gains in cowpea [Vigna unguiculata (L.) Walp.] under high-temperature stress

open access: yesBMC Plant Biology
Background Cowpea (Vigna unguiculata (L.) Walp.) is a crucial food and fodder crop in regions characterised by high temperatures. However, its reproductive stages are particularly sensitive to heat stress, leading to reduced pollen viability, pod set ...
Basavaraj PS   +12 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Biomass Estimation of mahogany (Swietenia macrophylla): An optimized weighted ensemble-based machine learning approach

open access: yesSmart Agricultural Technology
Accurate biomass estimation is crucial for assessing tree plantation health, productivity, and carbon dynamics, which underpin not only ecosystem service valuation but also carbon management.
Nobin Chandra Paul   +10 more
doaj   +1 more source

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