Results 61 to 70 of about 898,469 (266)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Multifunctional role of dietary copper to regulate stress-responsive gene for mitigation of multiple stresses in Pangasianodon hypophthalmus

Scientific Reports
It is an urgent needs to address climate change and pollution in aquatic systems using suitable mitigation measures to avoid the aquatic animals' extinction.
Neeraj Kumar, Supriya Tukaram Thorat, Samiksha R. Chavhan   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Comparative analysis of spatio-temporal rainfall patterns in the agro-climatic zones of India

Discover Atmosphere
Analyzing rainfall patterns over long periods is crucial to understand the impacts of climate change on water resources and agriculture. In this study, monthly, seasonal and annual rainfall trends in mainland agro-climatic zones (ACZs) of India were ...
Sonam Sah, RN Singh, B. Das, Santosha Rathod, Lata Vishnoi, A. K. Singh, Yogeshwar Singh, K. S. Reddy   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Tree shade mitigates stress and enhances chickpea productivity: Insights from an Emblica officinalis-based agroforestry system in semi-arid shallow Basaltic Deccan Plateau, India

Trees, Forests and People
Agroforestry influences microclimate and resource availability, particularly light, soil moisture, and nutrients, thus favouring the often growth of associated crops.
AR Chichaghare, SB Chavan, GB Rawale, AR Uthappa, VD Kakade, AS Morade, SS Changan, Nobin Paul, VB Gawade, PS Khapte, PS Basavaraj, RR Babar, Sandeep B Adavi, DD Nangare, CB Harisha, Hanamant M Halli, KS Reddy   +16 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Synergistic potential of deficit irrigation and grafted eggplant on wild rootstocks for enhanced growth, yield, and water productivity

Applied Water Science
As climate change intensifies water scarcity, sustainable strategies are essential for vegetable production under water-limited conditions. This study evaluates the potential of grafted eggplant onto wild rootstocks under deficit irrigation (DI) to ...
Pratapsingh S. Khapte, Lahu S. Chavan, Sushil S. Changan, Goraksha C. Wakchaure, Raghwendra A. Patil, Lalu Prasad Yadav, T. H. Singh, K. Sammi Reddy   +7 more
doaj   +1 more source