Results 81 to 90 of about 898,469 (266)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Dragon fruit cultivation in new areas: challenges, management strategies, and insights from India

Discover Agriculture
Dragon fruit is a highly nutritious fruit known for its ability to thrive in diverse soil and climate conditions worldwide, including India. While possessing considerable cultivation potential, dragon fruit yields in India, typically ranging from 15 to ...
V. D. Kakade, A. S. Morade, V. N. Salunkhe, K. M. Boraiah, Dinesh Jinger, Gaurav Singh, S. B. Chavan, Raj Kumar, Aliza Pradhan, Sonal Jadhav, Sachin Magar, Amol Patil, Akash Doke, Priyanka Jadhav, D. D. Nangare, K. Sammi Reddy   +15 more
doaj   +1 more source

Periodic colonization of Trichogramma japonicum for bio-control of yellow stem borer (Scirpophaga incertulas) in summer low-land rice (Oryza sativa)

The Indian Journal of Agricultural Sciences
Yellow stem borer [Scirpophaga incertulas (Walker)], is a major pest of low-land rice (Oryza sativa L.), causing 30–40% yield losses. The use of biological control agents to suppress yellow stem borer (YSB) population and damage across Asia includes ...
R K MURALI-BASKARAN, J SRIDHAR, K C SHARMA, LATA JAIN, P K GHOSH   +4 more
doaj   +1 more source

Stress Management in Hospitals

Sangyo Eiseigaku Zasshi, 2002
Job stress in employees in hospitals has been recognized as a key issue in the workplace. In this paper, characteristics of job stress in the medical profession, especially in doctors and nurses, and the effectiveness of stress management are overviewed. The important points in stress management in hospitals are summarized as follows: 1) improvement of
openaire   +3 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Curcumin as a protective agent against chromium and ammonia toxicity using molecular and biochemical approaches in fish

Scientific Reports
In aquatic ecosystems, metal and ammonia pollution pose major concern as they contaminate the environment and induces toxicity in fish. The present study addresses the toxicity induced by chromium (Cr) and ammonia (NH3) toxicity in fish and investigates ...
Amir Najir Mulla, Supriya Tukaram Thorat, Kalpana Chandramore, Prem Kumar, Kotha Sammi Reddy, Neeraj Kumar   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Assessing the effectiveness of AGRI UDAAN accelerator program on agri-startups in India: an integrated PCA and machine learning approach

Frontiers in Sustainable Food Systems
Agri-startups are transforming India’s agricultural landscape by providing innovative solutions and shifting youth from job seekers to job creators. Accelerator programs play a crucial role in strengthening these startups, yet systematic evaluations of ...
Navyasree Ponnaganti, Senthil S. Vinayagam, N. Sivaramane, Nobin Chandra Paul, K. Sammi Reddy, Dhananjay D. Nangare   +5 more
doaj   +1 more source