Results 91 to 100 of about 2,437,104 (305)

Ultrasonic measurement of stress in 2219-T87 aluminum plate [PDF]

The basic relationship of ultrasonic signal velocity to directional subsurface stress is reviewed. Inappropriateness of dependency on a single correlative value of constant for a three dimensional stress field in metallic materials is discussed ...
Clotfelter, W. N., Risch, E. R.
core   +1 more source

Cell contraction induces long-ranged stress stiffening in the extracellular matrix [PDF]

, 2017
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains largely unknown ...
Broedersz, Chase P., Guo, Ming, Han, Yu Long, Kamm, Roger, Lenz, Martin, Malandrino, Andrea, Ronceray, Pierre, Xu, Guoqiang   +7 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Experimental X-ray Stress Analysis Procedures for Ultra High Strength Materials [PDF]

X-ray stress analysis procedures for accurate measurement of elastic strain in high strength ...
Barkley, W. J., III, Clough, W. R., Jackman, L. A., Reilly, F. P., III, Woehrle, H. R.   +4 more
core   +1 more source

Neutrino-Deuteron Scattering in Effective Field Theory at Next-to-Next-to Leading Order [PDF]

, 2000
We study the four channels associated with neutrino-deuteron breakup reactions at next-to-next to leading order in effective field theory. We find that the total cross-section is indeed converging for neutrino energies up to 20 MeV, and thus our ...
A. Ali, B. Mueller, D.B. Kaplan, D.B. Kaplan, D.B. Kaplan, D.B. Kaplan, D.B. Kaplan, D.B. Kaplan, D.B. Kaplan, D.R. Phillips, G. Rupak, G.A. Aardsma, H.C. Lee, J.N. Bahcall, J.W. Chen, J.W. Chen, J.W. Chen, Jiunn-Wei Chen, K. Kubodera, M. Doi, M. Luke, M.J. Savage, M.N. Butler, Malcolm Butler, N. Tatara, P.F. Bedaque, P.F. Bedaque, R.B. Wiringa, S. Fleming, S. Fleming, S. Ying, S. Ying, S.D. Ellis, S.R. Beane, T.D. Cohen, T.D. Cohen, U. van Kolck, X. Kong, X. Kong, X. Kong, Xinwei Kong   +40 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Improved Use of Scatterometer Measurements by Using Stress-Equivalent Reference Winds

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2017
Numerical weather prediction (NWP) and buoy ocean surface winds show some systematic differences with satellite scatterometer and radiometer wind measurements, both in statistical results and in local geographical regions. It is possible to rescale these
Jos de Kloe, Ad Stoffelen, Anton Verhoef
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Full-field pulsed-magneto-photoelasticity - a description of the instrument

, 2006
This paper describes a novel instrument used for the analysis of full-field through-thickness stress distributions using the theory of magneto-photoelasticity (MPE) developed by Aben and Clarke et al. [ , , ].
Gibson, S., Jewell, G.W., Tomlinson, R.A.   +2 more
core   +1 more source