Results 81 to 90 of about 915,307 (312)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Determination of stress state in deep subsea formation by combination of hydraulic fracturing in situ test and core analysis: A case study in the IODP Expedition 319

, 2013
[1] In situ test of hydraulic fracturing (HF) provides the only way to observe in situ stress magnitudes directly. The maximum and minimum horizontal stresses, SHmax and Shmin, are determined from critical borehole pressures, i.e., the reopening pressure
Ito, Takatoshi, David F. Boutt, Ito, Hisao, Byrne, Timothy, Takatoshi Ito, Doan, Mai-Linh, Funato, Akio, Yasuyuki Kano, Lisa C. McNeill, Mai‐Linh Doan, Demian Saffer, McNeill, Lisa C., Saffer, Demian, Timothy Byrne, Lin, Weiren, Boutt, David F., Kano, Yasuyuki, Moe, Kyaw Thu, Kyaw Thu Moe, Akio Funato, Hisao Ito, Weiren Lin   +21 more
core   +1 more source

An improved pulsed electroacoustic system for space charge measurement under AC conditions [PDF]

, 2010
In this paper, an improved space charge measurement system based on the pulsed electro acoustic technique (PEA) is presented. The new system gives an essential way to examine the role of space charge in electrical aging process under AC conditions.
Z. Xu, J. Zhao, Xu, Z, Zhao, J, Xu, Z., Chen, G., G. Chen, Zhao, J., Chen, G   +8 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Measures of Psychosocial Stress and Stressful Exposures [PDF]

Arthritis Care & Research, 2020
Sarah L. Patterson, Sara Sagui‐Henson, Aric A. Prather   +2 more
openaire   +2 more sources

Assessment of residual stress using thermoelastic stress analysis

, 2011
The work described in this thesis considers the application of thermoelastic stress analysis (TSA) to theassessment of residual stresses in metallic materials. Residual stresses exist within almost all engineeringcomponents and structures.
Robinson, Andrew Ferrand
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Thermally Induced Rock Stress Increment And Rock Reinforcement Response

, 2016
The thermal heating caused by the deposition of spent nuclear fuel containers increases the in situ rock stress during disposal time. The thermal stress increase was modelled using thermo-mechanical modelling.
Hakala, Matti, Suikkanen, Johannes, Uotinen, Lauri, Nuijten, Guido, Siren, Topias, Ström, Jesse   +5 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source