Results 121 to 130 of about 2,437,104 (305)

High precision and real-time acquisition system for interface stress measurement in bridge bearing. [PDF]

Sci Rep, 2023
Cao X, Li G, Li Z, Sun W, Yan F, Jiang R.   +5 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Residual Stress Measurement Techniques for Metal Joints, Metallic Coatings and Components in the Railway Industry: A Review. [PDF]

Materials (Basel), 2022
Kendall O, Paradowska A, Abrahams R, Reid M, Qiu C, Mutton P, Yan W.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Stress Distribution Around Roadway of Kunyang No. 2 Phosphate Mine: Analytical Study and Field Verification

Applied Sciences
When excavating roadways in underground mines, stress redistribution within the surrounding rock mass leads to stress concentration and release. Should the concentrated stresses exceed the rock mass’s tensile or shear strength, rock deformation and ...
Zongyong Wang, Kepeng Hou, Menglai Wang, Hao Wu   +3 more
doaj   +1 more source

Development and Evaluation of a Multifrequency Ultrafast Doppler Spectral Analysis (MFUDSA) Algorithm for Wall Shear Stress Measurement: A Simulation and In Vitro Study. [PDF]

Diagnostics (Basel), 2023
Malone AJ, Cournane S, Naydenova I, Meaney JF, Fagan AJ, Browne JE.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Pipeline Hoop Stress Measurement Method Based on Propagation Path Correction of LCR Waves

Journal of Marine Science and Engineering
Pipelines are extensively used in offshore equipment. Accurate and non-destructive measurement of hoop stress conditions within pipes is critical for ensuring the integrity of offshore structures.
Bing Chen, Binbin Wang, Feifei Qiu, Chunlang Luo, Jiakai Chen, Guoqing Gou   +5 more
doaj   +1 more source

Stress Measurement in Primary Care: Conceptual Issues, Barriers, Resources, and Recommendations for Study. [PDF]

Psychosom Med, 2022
Wulsin LR, Sagui-Henson SJ, Roos LG, Wang D, Jenkins B, Cohen BE, Shah AJ, Slavich GM.   +7 more
europepmc   +1 more source