Results 121 to 130 of about 384,475 (307)

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Cognitive function in post-traumatic stress disorder [PDF]

Complaints of poor memory by individuals with posttraumatic stress disorder (PTSD) have engendered research into attention and memory functioning in this disorder.
Isaac, Claire L.
core  

MicroRNA regulation of persistent stress-enhanced memory

, 2020
Disruption of persistent, stress-associated memories is relevant for treating posttraumatic stress disorder (PTSD) and related syndromes, which develop in a subset of individuals following a traumatic event. We previously developed a stress-enhanced fear
Vinkers, Christiaan H, Stephanie E. Sillivan, Rutten, B.P.F., Courtney A. Miller, Rumbaugh, G., Berretta, Sabina, Boks, Marco P M, Sabina Berretta, Vermetten, E., Snijders, C., Jones, Meghan, Boks, Marco P. M., Jones, M., Jamieson, Sarah, Julian Krauskopf, Boks, M.P.M., Rutten, Bart P F, Nijs, L. de, Vinkers, Christiaan H., Ressler, K.J., Joseph, N.F., Snijders, Clara, Nadine F. Joseph, Sarah Jamieson, Miller, Courtney A, Krauskopf, Julian, Ressler, Kerry J, Christiaan H. Vinkers, Ressler, Kerry J., Geuze, E., de Nijs, Laurence, Jamieson, S., Elbert Geuze, Clara Snijders, Gavin Rumbaugh, Klengel, T., Klengel, Torsten, Kerry J. Ressler, Kleinjans, J., Berretta, S., Sillivan, Stephanie E, Meghan Jones, Bart P. F. Rutten, Miller, Courtney A., Marco P. M. Boks, Miller, C.A., Geuze, Elbert, Vermetten, Eric, Jos Kleinjans, Rumbaugh, Gavin, Rutten, Bart P. F., Sillivan, S.E., Kleinjans, Jos, Eric Vermetten, Vinkers, C.H., Sillivan, Stephanie E., Krauskopf, J., Torsten Klengel, Joseph, Nadine F, Laurence de Nijs, Joseph, Nadine F.   +60 more
core   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Exploring the role of working memory and understanding educational underachievement in anxiety and depression

, 2009
Research has shown that high levels of emotion are associated with lowered academic performance. However, the mechanisms involved in this relationship are as yet unclear. One potentially important process is the disruption of working memory.
Owens, Matthew
core  

An individual differences investigation of the relation between life event stress and working memory capacity [PDF]

, 2019
The effects of stress in both academic and social settings are well established. However, the effects of stress on cognitive functioning are less so.
NC DOCKS at Western Carolina University, Goller, Haley Grace   +1 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Chewing gum moderates multi-task induced shifts in stress, mood, and alertness: A re-examination

, 2011
The finding that chewing gum can moderate stress and mood changes following a multi-task cognitive stressor (Scholey, Haskell, Robertson, Kennedy, Milne, and Wetherell, 2009) was re-examined.
Jenks, R., Johnson, A. J., Cox, Martin, Christopher Miles, Miles, C., Albert, M., Andrew J. Johnson, Jenks, Rebecca A., Johnson, A.J., Johnson, Andrew, Martin Cox, Miles, Christopher, Michael Albert, Cox, M., Rebecca Jenks   +14 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source