Results 31 to 40 of about 4,353 (213)

Simulation of Stress Paths Derived from FEM Analysis in Triaxial Tests

open access: yesArchives of Civil Engineering, 2013
Reliable estimation of geotechnical parameters is often based on reconstruction of a complete loading process of subsoil on a specimen in laboratory tests.
Kowalska M.
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Deformation characteristics and shakedown behaviors of frozen silty clay under complex cyclic stress paths

open access: yesYantu gongcheng xuebao, 2023
The deformation characteristics and stability behaviors of frozen soil under complex cyclic stress paths play an important role in the long-term stability of cold region engineering.
WANG Yapeng 1, 2, 3, LI Guoyu 1, 2, 3, CHEN Dun 1, 3, MA Wei 1, 2, ZHANG Xuan 4
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Undrained deformation characteristic of saturated soft clay under traffic loading

open access: yesShuiwen dizhi gongcheng dizhi
Previous studies on the undrained deformation behavior of saturated soft clay under traffic loading usually ignored the effect of cyclic confining pressure.
Lei SUN, Yuke WANG
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Particle breakage characteristics of rockfills under complex stress paths

open access: yesYantu gongcheng xuebao, 2018
A series of conventional triaxial tests, isotropic compression tests and complex stress path triaxial tests are conducted to investigate the particle breakage characteristics of rockfills, which are evaluated quantitatively by using the relative breakage
WANG Yuan 1, ZHANG Sheng 2, AO Da-hua 2, YU Yu-zhen 1, SUN Xun 1
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Study of Mechanical Properties of Saline Soils under Different Stress Paths

open access: yesBuildings, 2023
The stress path is a critical factor affecting the mechanical properties of saline soils. In order to study the mechanical properties of saline soils under different stress paths, in situ saline soils in the Qian’an area of western Jilin province were ...
Shukai Cheng   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy