Results 51 to 60 of about 4,353 (213)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Effect of intermediate principal stress and minimum principal stress unloading stress path and rate on energy evolution of sandstone under true triaxial compression

open access: yesMeitan xuebao
In the process of deep coal mining, the unloading stress path and unloading rate of deep rock are complicated and changeable due to the influence of excavation and unloading.
Zhixi LIU   +3 more
doaj   +1 more source

Investigation of Lade-Kim Plastic Potential Applicability under Various Stress Paths for Rockfill Materials

open access: yesAdvances in Materials Science and Engineering, 2021
The dilatancy behavior of rockfill materials shows obvious stress path dependence. Lade-Kim plastic potential equation has been proposed for a long time to model the mechanical behavior of sand and concrete materials.
Liping Chen   +3 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

open access: yesArthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

Mobility and adjustments: Paths to the resolution of residential stress [PDF]

open access: yesDemography, 1990
Abstract In theory, residential mobility is a response to environmental stress only if households do not reduce dissatisfaction through other alternatives, such as housing improvements or repairs. Despite the attention given to stress-reducing alternatives, however, no attempt has been made to test empirically the residential ...
openaire   +2 more sources

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein   +7 more
wiley   +1 more source

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo   +4 more
wiley   +1 more source

Modified generalized plasticity model for rockfill materials

open access: yesYantu gongcheng xuebao, 2017
Within the framework of generalized plasticity theory, the plastic modulus is modified by adding two correction factors to enhance the adaptability of model under high confining stress, thus the generalized plasticity model for sand is successfully ...
BIAN Shi-hai 1,2,3, LI Guo-ying 2,3, WEI Kuang-min 2,3, ZHOU Jian 1
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

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