Results 51 to 60 of about 4,353 (213)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
In the process of deep coal mining, the unloading stress path and unloading rate of deep rock are complicated and changeable due to the influence of excavation and unloading.
Zhixi LIU +3 more
doaj +1 more source
The dilatancy behavior of rockfill materials shows obvious stress path dependence. Lade-Kim plastic potential equation has been proposed for a long time to model the mechanical behavior of sand and concrete materials.
Liping Chen +3 more
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source
Mobility and adjustments: Paths to the resolution of residential stress [PDF]
Abstract In theory, residential mobility is a response to environmental stress only if households do not reduce dissatisfaction through other alternatives, such as housing improvements or repairs. Despite the attention given to stress-reducing alternatives, however, no attempt has been made to test empirically the residential ...
openaire +2 more sources
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein +7 more
wiley +1 more source
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo +4 more
wiley +1 more source
Modified generalized plasticity model for rockfill materials
Within the framework of generalized plasticity theory, the plastic modulus is modified by adding two correction factors to enhance the adaptability of model under high confining stress, thus the generalized plasticity model for sand is successfully ...
BIAN Shi-hai 1,2,3, LI Guo-ying 2,3, WEI Kuang-min 2,3, ZHOU Jian 1
doaj +1 more source
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar +2 more
wiley +1 more source

