Results 51 to 60 of about 4,111,373 (256)

Simulation of Stress Paths Derived from FEM Analysis in Triaxial Tests

Archives of Civil Engineering, 2013
Reliable estimation of geotechnical parameters is often based on reconstruction of a complete loading process of subsoil on a specimen in laboratory tests.
Kowalska M.
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Undrained deformation characteristic of saturated soft clay under traffic loading

Shuiwen dizhi gongcheng dizhi
Previous studies on the undrained deformation behavior of saturated soft clay under traffic loading usually ignored the effect of cyclic confining pressure.
Lei SUN, Yuke WANG
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Deformation characteristics and shakedown behaviors of frozen silty clay under complex cyclic stress paths

Yantu gongcheng xuebao, 2023
The deformation characteristics and stability behaviors of frozen soil under complex cyclic stress paths play an important role in the long-term stability of cold region engineering.
WANG Yapeng 1, 2, 3, LI Guoyu 1, 2, 3, CHEN Dun 1, 3, MA Wei 1, 2, ZHANG Xuan 4
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Investigation of Tunnel Stress Path During Face Advancement

, 2007
Tunnel stress path during excavation was investigated in the study scope. The triple-center section is commonly designated for highway tunnels, but the analytical solution of the stress state for a non-circular tunnel section with multiple bench ...
W.-Y. Huang, C.-N. Chen
core   +1 more source

Particle breakage characteristics of rockfills under complex stress paths

Yantu gongcheng xuebao, 2018
A series of conventional triaxial tests, isotropic compression tests and complex stress path triaxial tests are conducted to investigate the particle breakage characteristics of rockfills, which are evaluated quantitatively by using the relative breakage
WANG Yuan 1, ZHANG Sheng 2, AO Da-hua 2, YU Yu-zhen 1, SUN Xun 1
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source