Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Path-integral simulation of graphene monolayers under tensile stress
Finite-temperature properties of graphene monolayers under tensile stress have been studied by path-integral molecular dynamics (PIMD) simulations.
Carlos P. Herrero +3 more
core +1 more source
Influences of temperature stress path on strength characteristics of undisturbed marine sediments
The difference between the room and the in-situ temperatures leads to that of the measured physical and mechanical parameters of marine sediments. Based on the temperature-controlled triaxial apparatus, the consolidated undrained shear tests are carried ...
ZHANG Xinrui 1, 3, KONG Gangqiang 1, YANG Qing 2
doaj +1 more source
Drained triaxial tests on mechanical properties of calcareous sand under various stress paths
The mechanical properties of calcareous sand are low in strength and easy to crush and have the characteristics of stress path dependence. In order to study the effects of different stress paths on the particle crushing and mechanical properties of ...
ZHANG Ji-ru, LUO Ming-xing, PENG Wei-ke, ZHANG Bi-wen
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Path Analysis on the Associations between Infertility, Stress, and Depression among Women in Surakarta, Central Java [PDF]
Background: In patriarchal societies like Indonesia, infertility is culturally considered as a problem of women. Most of the burden of infertility is borne by women because of a rapid decline in fertility with age, societal pressure and stigma ...
Indarto, Dono +2 more
core
Effects of Stress Path and Stress History on the Stiffness of Reconstituted London Clay
Soil behaviour is stress history dependent and stress path dependent and soil parameters, particularly those for stress-strain behaviour, measured in conventional triaxial tests may not represent the behaviour of soil in many civil engineering works.
Atkinson, J. H. +2 more
core +1 more source
Effect of stress path, size and shape on the optimum parameters of a brittle-ductile concrete model
The main purpose of this study is to investigate the effects of the stress path, size and shape of the specimen, on the optimum values of the plastic input parameters of Concrete Damaged Plasticity-CDP- model of the ABAQUS software.
Mojtaba Labibzadeh, Reza Hamidi
doaj +1 more source
Dilatancy behaviors and equation of calcareous sand considering stress path and particle breakage
The stress path and particle breakage have an impact on the dilatancy of calcareous sand. A series of drained triaxial compression tests with different stress paths and confining pressures are carried out to investigate the dilatancy of calcareous sand ...
LUO Ming-xing , ZHANG Ji-ru , LIU Xiao-xuan
doaj +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

