Results 51 to 60 of about 1,275,032 (266)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Effect of stress ratio on through thickness fatigue properties of unidirectional and quasi-isotropic thick CFRP laminates with toughened interlaminar layers

Nihon Kikai Gakkai ronbunshu, 2018
The effect of stress ratio on through thickness fatigue properties of thick carbon fiber reinforced plastic (CFRP) laminates with toughened interlaminar layers was evaluated.
Tomoki ARAI, Shinichiro FUKUSHIMA, Sen SEKI, Atsushi HOSOI, Hiroyuki KAWADA   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

True triaxial test and failure criterion of coal gangue concrete

Meitan xuebao
In view of the pollution caused by the large storage of coal gangue and the shortage of natural aggregate in concrete, using coal gangue as coarse aggregate is a reasonable way to solve the above problems.
Weiping ZHAO, Yuxiang HE, Kongliang JIANG, Jiaqi YANG, Yang XU, Jialong CHEN   +5 more
doaj   +1 more source

Experimental Study on the Dynamic Modulus and Damping Ratio of Compacted Loess under Circular Dynamic Stress Paths

Advances in Civil Engineering, 2021
Dynamic loads such as earthquakes and traffic will simultaneously generate vertical dynamic stress and horizontal shear stress in the foundation soil. When the vertical dynamic stress amplitude is twice the horizontal shear dynamic stress amplitude, and ...
Liguo Yang, Shengjun Shao, Zhi Wang
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Effect of Multiple Factors on the Fatigue Crack Growth Behavior of DH36 Steel in Arctic Environment

Journal of Marine Science and Engineering
In Arctic regions, ship structures face low temperatures, overloads, thickness effects, and fluctuating stress ratios, which significantly influence the fatigue crack growth (FCG) behavior of marine steels.
Kaiqing Qiao, Zhijie Liu, Zhenyu Sun, Qiuyu Guo, Xiaobang Wang   +4 more
doaj   +1 more source

Multiple Fully Stressed Structural Designs and the Stress Ratio Method

Computer-Aided Civil and Infrastructure Engineering, 1995
Some structures are capable of being proportioned in several different ways such that each one is a fully stressed design. This paper investigates the nature of these multiple fully stressed designs, the relationships that exist between them, and the behavior of the stress ratio method when applied to the sizing of such structures.
Scott A. Burns, Michael W. Orlet, Mark A. Raschke   +2 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source