Results 61 to 70 of about 1,360,531 (316)

Effects of inclusion size and stress ratio on fatigue strength for high-strength steels with fish-eye mode failure

, 2013
Experimental results indicate that the fatigue life reduces by about two orders of magnitude when inclusion size doubles. Then, a model is proposed for predicting the fatigue strength of high-strength steels with fish-eye mode failure based on the ...
Hong, YS (reprint author), Chinese Acad Sci, State Key Lab Nonlinear Mech, Inst Mech, Beijing 100190, Peoples R China., Lei ZQ(雷铮强), Sun CQ(孙成奇), Xie JJ(谢季佳), Hong YS(洪友士)   +4 more
core   +1 more source

Short- and long-term adaptation to ethanol stress and its cross-protective consequences in Lactobacillus plantarum [PDF]

, 2011
This paper describes the molecular responses of Lactobacillus plantarum WCFS1 toward ethanol exposure. Global transcriptome profiling using DNA microarrays demonstrated adaptation of the microorganism to the presence of 8% ethanol over short (10-min and ...
Kleerebezem, M., Abee, T., Tempelaars, M.H., Kleerebezem, M. (author), Marco, M.L. (author), Hermien Van Bokhorst-van De Veen, Van Bokhorst-van de Veen, H., Marcel Tempelaars, Tempelaars, M., Abee, T. (author), Michiel Kleerebezem, Bron, P.A. (author), Maria L. Marco, Peter A. Bron, Bokhorst-van de Veen, H., van, Tjakko Abee, Bron, P.A., Marco, M.L., Tempelaars, M. (author), Van Bokhorst-van de Veen, H. (author)   +19 more
core   +1 more source

Testing and modelling the fatigue behaviour of GFRP composites – Effect of stress level, stress concentration and frequency [PDF]

, 2020
The effects of stress level, stress concentration and frequency on the fatigue life of glass fibre reinforced polymer (GFRP) composites have been investigated under tension-tension fatigue at a stress ratio of 0.1.
Salih, Choman, Yu, Peng, Manalo, Allan, Peauril, Joshua, Schubel, Peter, Ferdous, Wahid, Heyer, Tom, Reddy, Kakarla Raghava   +7 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

A simple fatigue methodology for filled natural rubbers under positive and negative R ratios

Materials Research Express
This paper suggests a simple methodology to optimize the uniaxial fatigue predictions for filled natural rubbers. In this study, the stress ratio $R$ effect on rubber fatigue life is investigated numerically.
Salma Belkhiria, Anis Abroug, Raouf Fathallah   +2 more
doaj   +1 more source

A Non-Singular Analytical Technique for Reinforced Non-Circular Holes in Orthotropic Laminate

International Journal of Applied Mechanics and Engineering, 2020
The intricacy in Lekhnitskii’s available single power series solution for stress distribution around hole edge for both circular and noncircular holes represented by a hole shape parameter ε is decoupled by introducing a new technique.
Pradeep Mohan, R. Ramesh Kumar
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Children's stress-related reports and stress biomarkers interact in their association with metabolic syndrome risk

, 2018
The purpose was to examine the cross-sectional associations of stress-related reports and stress biomarkers with metabolic syndrome (MetS) risk in children while also testing the interaction between stress biomarkers and stress reports.
Marild, Staffan, De Henauw, S., Matthys, Dante, Thumann, B., Thumann, Barbara, Michels, Nathalie, Stefaan De Henauw, Nathalie Michels, Staffan Marild, Mårild, Staffan,, Michels, N., De Henauw, Stefaan, Dante Matthys, Barbara Thumann, Matthys, D.   +14 more
core   +1 more source

Study on Crack Propagation of Steel for Coiled Tubing Based on Extended Finite Element Method

Shiyou jixie, 2019
Fatigue crack propagation is the main cause of coiled tubing failure. To address the cumbersome testing study work of the crack propagation process of steel for coiled tubing, the extended finite element method (XFEM) was introduced for analysis.
Shi Jiangang, Jiang Zhenxin, Xiang Dongmei, Zhang Jie, Guan Feng, Wang Zhen   +5 more
doaj