Results 61 to 70 of about 1,275,032 (266)

Analisis potensi likuifaksi berdasarkan data penyelidikan tanah standard penetration test (SPT) (studi Kasus cross taxiway timur Bandara Soekarno Hatta Tangerang)

open access: yesTeknika, 2020
Fenomena likuifaksi sering terjadi setelah kejadian gempa di beberapa tempat. Likuifaksi pada tanah dapat menyebabkan kerusakan yang parah bagi bangunan yang berada di atasnya, sehingga kerugian yang ditimbulkan sangat besar.
Enden Mina   +2 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Modelling the yield stress and the Poisson’s ratio of glassy polymers

open access: yese-Polymers, 2009
Abstract We have recently reported that the volumetric as well as the viscoelastic intricacies of mechanically stimulated glasses can be predicted by coupling the structural relaxation kinetics and viscoelastic response [1, 2, 3]. Here, it will be shown that our approach can be extended to predict the stressstrain ...
D'AMORE, Alberto   +2 more
openaire   +4 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Fatigue Fracture Behaviors of Transparent Polycarbonate Materials

open access: yesCailiao gongcheng, 2017
The effect of the different stress ratios (R) and annealing treatment on the fatigue properties of the transparent polycarbonate (PC) sheet and the mechanism behind were studied, the fatigue crack propagation (FCP) process and mechanism were analyzed ...
ZHANG Xiao-wen   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Fatigue Crack Propagation Property of YB-DM-10 Directional PMMA

open access: yesCailiao gongcheng, 2018
The threshold value of stress intensity factor range was acquired according the study of fatigue crack propagation property of directional PMMA (YB-DM-10).
ZHAO Jing-yun   +4 more
doaj   +1 more source

The Ratio of Working Stress to Allowable Stress of Structural Members of Wooden Houses II.

open access: yesMokuzai Gakkaishi, 2008
耐積雪等級が一般地域に建設された3棟の木造住宅の梁に生じる各種応力および最大たわみを算出し,許容応力度およびたわみ制限に対する負担率をそれぞれ求め,各梁において最大負担率を示す各応力・変形条件および荷重継続期間を調べた。その結果,以下の結論を得た。1)最大負担率が80%を越す例外的な梁もいくつか見られたが,平均すると約7割の梁は負担率が20%以下であり,強度的な余裕は充分にあった。2)小屋梁の多くでは「最大たわみ」によって最大負担率が決定する傾向があった。これは,小屋梁に断面の小さい梁を用いることが居住性に悪影響をもたらす訳ではないため,設計者が経済的な有利さを考慮してそれらを選択したと推察される。3)梁のスパン中間に上階の耐力壁が下階の柱無しに載ることにより,強度的に余裕が乏しい梁も存在しうる ...
Hideki Aoi   +3 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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