Results 81 to 90 of about 1,360,531 (316)
, 2014 Background: It is suggested the declining male birth proportion in some industrialized countries is linked to ubiquitous endocrine disruptor exposure. Stress and advanced parental age are determinants which frequently present positive findings.
McDonald, Ewan +6 more
core +1 more source
AerospaceCrack growth analysis is essential for probabilistic damage tolerance assessment of aeroengine life-limited parts. Traditional crack growth models directly establish the stress ratio–crack growth rate or crack opening stress relationship and focus less ...
Guo Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Dependence of sonic velocity on effective stress in fine-grained sediments [PDF]
, 2005 Overpressure estimation methods that use sonic velocity as a proxy for porosity only account for excess pressure due to disequilibrium compaction; the influence of unloading processes in generating larger excess pressure observed in most basins is ...
Mavatikua, Lubanzadio
core
Effect of stress ratio on the very high-cycle fatigue failure mechanism of TC4 titanium alloy
工程科学学报, 2019 As technology has developed along with the increasing mechanical demands placed upon it, the need for fatigue exceeding 107 cycles or even longer for machines and components is necessary, not only for safety and reliability, but also for minimizing the ...
GAO Ning, LI Wei
doaj +1 more source
Modelling the yield stress and the Poisson’s ratio of glassy polymers
e-Polymers, 2009 Abstract We have recently reported that the volumetric as well as the viscoelastic intricacies of mechanically stimulated glasses can be predicted by coupling the structural relaxation kinetics and viscoelastic response [1, 2, 3]. Here, it will be shown that our approach can be extended to predict the stressstrain ...
D'AMORE, Alberto +2 more
openaire +4 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2020 Reactive oxygen and nitrogen species-mediated cellular aging has been linked to diseases such as atherothrombosis and cancer. Although pentraxin 3 (PTX3) is associated with aging-related diseases via TLR4-dependent anti-inflammatory effects, its ...
Michael Whitehurst +6 more
core +1 more source
Effect of Stress Ratio on Fatigue Crack Growth Behavior of Ti-6Al-2Zr-1Mo-1V Alloy
Journal of Aeronautical Materials, 2018 The fatigue crack growth behaviors of Ti-6.5Al-2Zr-1Mo-1V titanium alloy at different positive stress ratios (R = 0.1, 0.3 and 0.5) were investigated at room temperature.
JI Yingping, WU Sujun
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source