Results 71 to 80 of about 1,360,531 (316)

Research on Fatigue Crack Growth Rate Prediction of 2024-T3 Aluminum Alloy Friction Stir Welded Joints Driven by Machine Learning

Aerospace
Fatigue crack propagation in friction stir welded joints significantly affects aircraft structural integrity. This study investigates the influence of welding speed, rotational speed, specimen thickness, loading frequency, and stress ratio on the fatigue
Yanning Guo, Na Sun, Wenbo Sun, Xiangmiao Hao   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Experimental Study on the Dynamic Modulus and Damping Ratio of Compacted Loess under Circular Dynamic Stress Paths

Advances in Civil Engineering, 2021
Dynamic loads such as earthquakes and traffic will simultaneously generate vertical dynamic stress and horizontal shear stress in the foundation soil. When the vertical dynamic stress amplitude is twice the horizontal shear dynamic stress amplitude, and ...
Liguo Yang, Shengjun Shao, Zhi Wang
doaj   +1 more source

Analysis of Stress Ratio and Stress Regime in West Java

Indonesian Journal on Geoscience
This study actively investigates stress ratios, principal stress orientations, and stress regimes in the West Java Province, Indonesia, by simultaneously inverting both the stress tensor and fault orientations from 232 moment tensors. It identifies diverse stress regimes, including normal and reverse faulting in the subduction zone, as well as mixed ...
Anne M. Sirait, Kadek Hendrawan Palgunadi, Andrean V. H. Simanjuntak, Nadhira Rahmania, Izaaz Naufal, Muhammad Nanda Rizqi Dhiarofa, Akhlaqul Karimah, Rafi Sadam Al-Ghifari, Azhari Ramadhani, Farrastha Hady Hady, Dwa Desa Warnana, Wiwit Suryanto   +11 more
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Multiple Fully Stressed Structural Designs and the Stress Ratio Method

Computer-Aided Civil and Infrastructure Engineering, 1995
Some structures are capable of being proportioned in several different ways such that each one is a fully stressed design. This paper investigates the nature of these multiple fully stressed designs, the relationships that exist between them, and the behavior of the stress ratio method when applied to the sizing of such structures.
Scott A. Burns, Michael W. Orlet, Mark A. Raschke   +2 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Analisis potensi likuifaksi berdasarkan data penyelidikan tanah standard penetration test (SPT) (studi Kasus cross taxiway timur Bandara Soekarno Hatta Tangerang)

Teknika, 2020
Fenomena likuifaksi sering terjadi setelah kejadian gempa di beberapa tempat. Likuifaksi pada tanah dapat menyebabkan kerusakan yang parah bagi bangunan yang berada di atasnya, sehingga kerugian yang ditimbulkan sangat besar.
Enden Mina, Rama Indera Kusuma, Kiki Ariandhika Muzaky   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source