Results 91 to 100 of about 8,553,788 (398)

Chemotherapeutic Resistance: Surviving Stressful Situations [PDF]

Cancer Research, 2011
Abstract Chemotherapeutic regimens involve the systemic administration of genotoxic compounds that induce cancer cell death via well-established DNA damage response signaling networks. Less understood is how the treatment of other cell types within the tumor microenvironment affects the therapeutic response.
Gilbert, Luke Andrew, Hemann, Michael
openaire   +5 more sources

OsSCYL2 is Involved in Regulating ABA Signaling-Mediated Seed Germination in Rice

Plants
Seed germination represents a multifaceted biological process influenced by various intrinsic and extrinsic factors. In the present study, our investigation unveiled the regulatory role of OsSCYL2, a gene identified as a facilitator of seed germination ...
Minyan Xu, Wei Zhang, Yuhuan Jiao, Qing Yang, Meng Chen, Hu Cheng, Beijiu Cheng, Xin Zhang   +7 more
doaj   +1 more source

Identification and characterization of the BZR transcription factor family and its expression in response to abiotic stresses in Zea mays L. [PDF]

, 2017
Brassinosteroids (BRs) are plant specific steroidal hormones that play diverse roles in regulating a broad spectrum of plant growth and developmental processes, as well as, in responding to various biotic and abiotic stresses. Extensive research over the
Manoli, Alessandro, Quaggiotti, Silvia, Trevisan, Sara, Varotto, Serena   +3 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Wheat TaTIFY3B and TaTIFY10A play roles in seed germination and abiotic stress responses in transgenic Arabidopsis and rice

BMC Plant Biology
Background Seed germination is a key process in the plant life cycle that affects the vegetative and reproductive stages of plants. Although the JAZ gene family has been characterized in many plants, the relationship between the JAZ gene and seed ...
Hanxi Liu, Yaxin Yao, Jiayang Ma, Shaoyu Wang, Song Li, Weiwei Wang, Xinmiao Yu, Fengli Sun, Chao Zhang, Yajun Xi   +9 more
doaj   +1 more source

Stress-corrosion characteristics of aluminum casting alloy M-45 [PDF]

, 1968
Evaluation of the stress-corrosion characteristics of aluminum alloy M-45 shows that the most favorable artificial aging cycle for this alloy, with regard to optimum strength and stress-corrosion resistance, appears to be 400 degrees F for 12 ...
Lovoy, C. V.
core   +1 more source

NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

eLife, 2017
Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, and ...
Collin Yvès Ewald, John M. Hourihan, John M. Hourihan, Monet S Bland, Monet S Bland, Carolin Obieglo, Carolin Obieglo, I. Katic, L. E. M. Mazzeo, L. E. M. Mazzeo, Joy Alcedo, Joy Alcedo, T. K. Blackwell, T. K. Blackwell, N. Hynes   +14 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Whole-Genome Duplication and Purifying Selection Contributes to the Functional Redundancy of Auxin Response Factor (ARF) Genes in Foxtail Millet (Setaria italica L.)

International Journal of Genomics, 2021
Auxin response factors (ARFs) play crucial roles in auxin-mediated response, whereas molecular genetics of ARF genes was seldom investigated in Setaria italica, an important crop and C4 model plant. In the present study, genome-wide evolutionary analysis
You Chen, Bin Liu, Yujun Zhao, Wenzhe Yu, Weina Si   +4 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source