Results 101 to 110 of about 9,272,105 (348)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Stress sensitivity of tight reservoirs during pressure loading and unloading process
Petroleum Exploration and Development, 2019 Laboratory experiments were conducted on laboratory-made tight cores to investigate the stress-dependent permeability hysteresis of tight reservoirs during pressure loading and unloading process. Based on experiment results, and Hertz contact deformation
Nai Cao, G. Lei
semanticscholar +1 more source
Stress Sensitivity in Psychosis [PDF]
, 2018 During the last century the concept of "stress" has taken a central position in both preclinical and clinical research. Its implications range from an organism's most basic survival tactics to physical and mental well-being. In humans, stress is implicated in the epidemiology of a broad range of mental disorders, urging for a better understanding of ...
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Macro stress testing with sector specific bankruptcy models [PDF]
, 2008 This paper employs the methodology of Wilson (1997) on Hungarian data to conduct a macro stress test in relation to banks' corporate loan portfolio. First, sector specific models of bankruptcy are estimated, where the bankruptcy frequency is linked to ...
Valentinyi-Endresz, Marianna +1 more
core
Geofluids, 2019 Shale reservoirs are characterized by low permeability and natural fractures. In the process of reservoir development, the working fluid enters the reservoir. This may result in the formation of new fractures or expansion of natural fractures. When shale
Xiangjun Liu +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Empirical Relationships among Trauma Exposure, Anxiety Sensitivity, and Post Traumatic Stress Disorder [PDF]
, 2020 This review synthesized and critically reviewed empirical studies that assessed relationships among trauma exposure, anxiety sensitivity (AS), and Post Traumatic Stress Disorder (PTSD).
Beam, Payton +3 more
core +1 more source