Results 121 to 130 of about 1,417,340 (268)

The Effect of the Stress State, Testing Temperature, and Hardener Composition on the Strength of an AlMg5/Epoxy Metal-Polymer Joint. [PDF]

Materials (Basel), 2022
Smirnov S, Konovalov D, Vichuzhanin D, Veretennikova I, Pestov A, Osipova V.   +5 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Involvement of the Renin-Angiotensin System in Stress: State of the Art and Research Perspectives. [PDF]

Curr Neuropharmacol, 2022
Correa BHM, Becari L, Fontes MAP, Simões-E-Silva AC, Kangussu LM.   +4 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Effects of Geometry and Loading Mode on the Stress State in Asphalt Mixture Cracking Tests. [PDF]

Materials (Basel), 2022
Li Y, Xuan W, Rahman A, Ding H, Yusupov B.   +4 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on the evaluation model of pilots' in-flight stress state based on flight critical events. [PDF]

Front Physiol
Shang L, Lu M, Qian C, Wanyan X, Zhou Y, Liu S.   +5 more
europepmc   +1 more source

Skin-to-skin contact to improve premature mothers' anxiety and stress state: A meta-analysis. [PDF]

Matern Child Nutr, 2021
Cong S, Wang R, Fan X, Song X, Sha L, Zhu Z, Zhou H, Liu Y, Zhang A.   +8 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Analyses of Stress-State-Dependent Ductile Damage and Fracture Behavior of Zirconium. [PDF]

Materials (Basel)
Pan B, Zhu L, Wei Z, Tekkaya B, Stebner S, Münstermann S.   +5 more
europepmc   +1 more source