Stress State Classification Based on Deep Neural Network and Electrodermal Activity Modeling. [PDF]
Sensors (Basel), 2023 Vasile F +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Studying the Plastic Deformation of Cu-Ti-C-B Composites in a Favorable Stress State. [PDF]
Materials (Basel), 2023 Pugacheva N +3 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BMC Plant BiologyBackground Seed germination is a key process in the plant life cycle that affects the vegetative and reproductive stages of plants. Although the JAZ gene family has been characterized in many plants, the relationship between the JAZ gene and seed ...
Hanxi Liu +9 more
doaj +1 more source
Transcriptomic Analysis of the Aged Nulliparous Mouse Ovary Suggests a Stress State That Promotes Pro-Inflammatory Lipid Signaling and Epithelial Cell Enrichment. [PDF]
Int J Mol Sci, 2023 Chacón C +3 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Phytopathology ResearchKiwifruit bacterial canker (KBC), caused by Pseudomonas syringae pv. actinidiae (Psa), poses a severe threat to the global kiwifruit industry, highlighting the urgent need to elucidate its pathogenic mechanisms. Cyclic diguanylate monophosphate (c-di-GMP)
Yudi Wang +7 more
doaj +1 more source
Effect of Process Parameters on the Crystallinity and Geometric Quality of Injection Molded Polymer Gears and the Resulting Stress State during Gear Operation. [PDF]
Polymers (Basel), 2023 Zorko D.
europepmc +1 more source