Influence of Grain Orientation and Grain Boundary Features on Local Stress State of Cu-8Al-11Mn Alloy Investigated Using Crystal Plasticity Finite Element Method. [PDF]
Materials (Basel), 2022 Zheng C +6 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Seasonal Changes and Relationships in Training Loads, Neuromuscular Performance, and Recovery and Stress State in Competitive Female Soccer Players. [PDF]
Front Sports Act Living, 2021 Ishida A +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Application of a 3D-Printed Part with Conformal Cooling in High-Pressure Die Casting Mould and Evaluation of Stress State During Exploitation. [PDF]
Materials (Basel)Małysza M +7 more
europepmc +1 more source
Adjusting the Residual Stress State in Wire Drawing Products via In-Process Modification of Tool Geometries. [PDF]
Materials (Basel), 2021 Baumann M +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Combination of Diane-35 and Cangfu Daotan Wan Effectively Ameliorates Inflammatory Response, Stress State, and Hormone Levels in Patients with Polycystic Ovary Syndrome (PCOS), Leading to Significant Improvement in Clinical Treatment Outcomes. [PDF]
Int J Womens HealthChen L +6 more
europepmc +1 more source
Contrasting the Role of Pores on the Stress State Dependent Fracture Behavior of Additively Manufactured Low and High Ductility Metals. [PDF]
Materials (Basel), 2021 Wilson-Heid AE, Furton ET, Beese AM.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source