Results 91 to 100 of about 1,255,877 (306)

How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? [PDF]

, 2015
This work was financially support by a Marie Curie Initial Training Network grant, “Understanding the evolutionary origin of biological diversity” (ITN-2008–213780 SPECIATION), grants from the Academy of Finland to A.H.
A Hoikkala, A Laiho, A Martin, A Sasson, AA Hoffmann, AL Majumder, AR McCune, B Katz, BJ Sinclair, C Canestro, CJ Reaume, CP Downes, D Arbuthnott, D Bell-Pedersen, D J Parker, DW Huang, DW Huang, FA Loewus, H Colinet, H Colinet, HA MacMillan, J Overgaard, J Zhang, JR Hazel, K Xu, KB Storey, KY Xu, L Kivivuori, L Vesala, L Vesala, L Vesala, LH Throckmorton, M G Ritchie, M Kankare, M Kim, M Reis, M Watanabe, M Watanabe, MC Magnone, MD Robinson, MD Robinson, MJ Fitzpatrick, MK Jones, MV Rockman, NM Teets, PR Senthilan, PW Hochachka, R David, R Morales-Hojas, R Niwa, RE Lee, RE Lee, RM Robich, RW Salt, S Anders, S Fowler, S Sahar, S Tweedie, V Kellermann, V Kostal, V Koštál, V Koštál, Vr Koštál, W Block, W Huang, WJ Heitler, WL Shen, X Huang, XL Guan, Y Benjamini, ZD Liu   +70 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Emerging Strategies for Aflatoxin Resistance in Peanuts via Precision Breeding

Toxins
Aflatoxin contamination, primarily caused by Aspergillus flavus, poses a significant threat to peanut (Arachis hypogaea L.) production, food safety, and global trade. Despite extensive efforts, breeding for durable resistance remains difficult due to the
Archana Khadgi, Saikrisha Lekkala, Pankaj K. Verma, Naveen Puppala, Madhusudhana R. Janga   +4 more
doaj   +1 more source

Transgressivity in Key Functional Traits Rather Than Phenotypic Plasticity Promotes Stress Tolerance in A Hybrid Cordgrass [PDF]

, 2019
Hybridization might promote offspring fitness via a greater tolerance to environmental stressors due to heterosis and higher levels of phenotypic plasticity.
Castillo Segura, Jesús Manuel, Drenovsky, Rebecca E., Gallego Tévar, Blanca, Grewell, Brenda J.   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Acetic acid: a cheap but chief metabolic regulator for abiotic stress tolerance in plants

Stress Biology
As sessile organisms, plants constantly face a variety of abiotic stresses, such as drought, salinity, and metal/metalloid toxicity, all of which possess significant threats to plant growth and yield potential.
Md. Mezanur Rahman, Sanjida Sultana Keya, Abira Sahu, Aarti Gupta, Anuradha Dhingra, Lam-Son Phan Tran, Mohammad Golam Mostofa   +6 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Mindfulness-based stress reduction in patients with interstitial lung diseases: a pilot, single-centre observational study on safety and efficacy [PDF]

, 2015
open11siBackground Chronic, progressive respiratory symptoms are associated with great psychological and emotional impact in patients suffering from interstitial lung disease (ILD).
CERRI, Stefania, FERRARI, ROBERTO, Garuti, Martina, LUPPI, Fabrizio, MONTANARI, GLORIA, Ori, Margherita, Petropulacos, Kyriakoula, Poletti, Stefano, Ricchieri, Maria Pia, RICHELDI, Luca, SGALLA, Giacomo   +10 more
core   +1 more source

Salinity Stress and Salt Tolerance

, 2011
Salinity is one of the most serious factors limiting the productivity of agricultural crops, with adverse effects on germination, plant vigour and crop yield (R Munns & Tester, 2008). Salinization affects many irrigated areas mainly due to the use of brackish water.
CARILLO P, ANNUNZIATA M. G, PONTECORVO, Giovanni, FUGGI A, WOODROW P   +4 more
openaire   +4 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source