Results 71 to 80 of about 2,718,585 (285)
Sparingly glued tolerances [PDF]
, 2015 We introduce the notion of sparingly glued tolerances for lattices and then count their numbers in case of finite chains.
Górnicka, A., Tyrala, I., Grygiel, J.
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Stream invertebrates and water temperature : evaluating thermal tolerances in the Cape floristic region (South Africa) - implications of climate change [PDF]
, 2009 Includes bibliographical references.Temperature is an important environmental variable for aquatic invertebrates as it affects their development, reproduction and survival.
Ketley, Zoma Anne
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Evolutionary Applications, 2021 Cities are often hotter and drier compared with nearby undeveloped areas, but how organisms respond to these multifarious stressors associated with urban heat islands is largely unknown.
Aaron R. Yilmaz +2 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Some basics on tolerances [PDF]
In this note we deal with sensitivity analysis of combinatorial optimization problems and its fundamental term, the tolerance. For three classes of objective functions (?, ?, MAX) we prove some basic properties on upper and lower tolerances. We show that
Jäger, G. +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Combinatorial optimization tolerances calculated in linear time [PDF]
For a given optimal solution to a combinatorial optimization problem, we show, under very natural conditions, the equality of the minimal values of upper and lower tolerances, where the upper tolerances are calculated for the given optimal solution and ...
Goldengorin, Boris, Sierksma, Gerard
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New Approaches for Crop Genetic Adaptation to the Abiotic Stresses Predicted with Climate Change
Agronomy, 2013 Extreme climatic variation is predicted with climate change this century. In many cropping regions, the crop environment will tend to be warmer with more irregular rainfall and spikes in stress levels will be more severe.
Robert Redden
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