Results 71 to 80 of about 17,964 (291)

Screening Oat Genotypes for Tolerance to Salinity and Alkalinity

Frontiers in Plant Science, 2018
A set of four experiments was conducted to develop methods for screening oat tolerance to salt and alkali and the following results were obtained.
Jianhui Bai, Jianhui Bai, Weikai Yan, Yuqing Wang, Qiang Yin, Jinghui Liu, Charlene Wight, Baoluo Ma   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Wheat improvement for nutritional quality and abiotic stress tolerances

Discover Plants
Hunger, malnutrition, and climate change (CC) are the prime concerns impacting a substantial fraction of the world’s population. Wheat is one of the notable staple foods imperatives for supporting global food and nutrition security.
Debanjana Saha, Krishna Mishra, Chinmayee Pattnayak, Prajjal Dey, Mahendra Singh, Monika Yadav, Chitrangna Singh, Rajesh Kumar Singhal   +7 more
doaj   +1 more source

Autophagy, a conserved mechanism for protein degradation, responds to heat and other abiotic stresses in Capsicum annuum L.

Frontiers in Plant Science, 2016
Abiotic stresses negatively affect plants growth and development by inducing protein denaturation, and autophagy degrades the damaged proteins to alleviate their toxicity, however, little is known about the involvement of autophagy in pepper (Capsicum ...
Yufei eZhai, Meng eGuo, Hu eWang, Jinping eLu, Jinhong eLiu, Chong eZhang, Zhen-Hui eGong, Minghui eLu   +7 more
doaj   +1 more source

Heterologous Expression of Three Ammopiptanthus mongolicus Dehydrin Genes Confers Abiotic Stress Tolerance in Arabidopsis thaliana

Plants, 2020
Ammopiptanthus mongolicus, a xerophyte plant that belongs to the family Leguminosae, adapts to extremely arid, hot, and cold environments, making it an excellent woody plant to study the molecular mechanisms underlying abiotic stress tolerance.
Hongwei Cui, Yang Wang, Tingqiao Yu, Shaoliang Chen, Yuzhen Chen, Cunfu Lu   +5 more
doaj   +1 more source

Towards Understanding the Transcriptional Control of Abiotic Stress Tolerance Mechanisms in Food Legumes

, 2015
A multitude of environmental and subsoil conditions cause abiotic constraints to the growth and productivity of legume food species. These stresses often occur simultaneously, leading to compounded effects of low and unreliable yields.
Saleem Khan, Ford, R, Khan, S, Mantri, N, Rebecca Ford, Mantri, Nitin, Ford, Rebecca, Khan, Saleem, Nitin Mantri   +8 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Mechanisms and evolution of resistance to environmental extremes in animals

EvoDevo, 2019
When animals are exposed to an extreme environmental stress, one of three possible outcomes takes place: the animal dies, the animal avoids the environmental stress and survives, or the animal tolerates the environmental stress and survives.
Thomas C. Boothby
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Evidence for the evolution of thermal tolerance, but not desiccation tolerance, in response to hotter, drier city conditions in a cosmopolitan, terrestrial isopod

Evolutionary Applications, 2021
Cities are often hotter and drier compared with nearby undeveloped areas, but how organisms respond to these multifarious stressors associated with urban heat islands is largely unknown.
Aaron R. Yilmaz, Sarah E. Diamond, Ryan A. Martin   +2 more
doaj   +1 more source